Results 71 to 80 of about 9,350 (117)

Study on Hepatotoxicity of Benzophenone-3 at Environmental Concentration in Postpartum Mice

open access: yesToxics
Benzophenone-3 (BP-3), a widely used ultraviolet absorber in various scenarios, exhibits estrogenic toxicity at environmental concentrations—as demonstrated in our prior work.
Huai-Fan Zhai   +10 more
doaj   +1 more source

Asia Pacific Congress on Fertility Preservation

open access: yes
"Exploring the frontier of ovarian tissue cryopreservation and transplantation" "A multidisciplinary panel discussion on fertility ...
Asia Pacific Congress on Fertility Preservation   +1 more
core  

Paternal ribosome biogenesis dysfunction caused by cyclophosphamide-busulfan chemotherapy contributes to early embryonic developmental impairment in mice

open access: yesJournal of Translational Medicine
Background Combined cyclophosphamide (CTX) and busulfan (BUS) chemotherapy, while effective against malignancies, poses significant risks to male reproductive health. This study systematically investigates the proteomic basis underlying CTX + BUS-induced
Xin Li   +7 more
doaj   +1 more source

Quercetin Attenuates Iron Overload-Induced Renal Injury via Activating Nrf2/xCT/GPX4 Signaling to Inhibit Ferroptosis

open access: yesLife
Iron overload, a key driver of ferroptosis, results from excessive iron accumulation in tissues and contributes to organ injury, including renal dysfunction.
Xiaoyi Wang   +8 more
doaj   +1 more source

Fertility Preservation

open access: yes, 2018
Gonad cells (oocyte or spermatozoon) and tissues (ovary, testicle) are protected from gonadotoxic exposure to ensure the continuity of fertility due to medical interventions such as chemotherapy, radiotherapy, surgery, and the other non-oncological ...
Akdemir, Nermin
core   +1 more source

Metformin modulates the TXNIP-NLRP3-GSDMD pathway to improve diabetic bladder dysfunction

open access: yesScientific Reports
To validate the therapeutic efficacy of metformin on diabetic bladder dysfunction (DBD) and further elucidate whether the TXNIP-NLRP3-GSDMD axis serves as a target for metformin in ameliorating DBD. C57BL/6J mice were induced with diet-induced obesity by
Bincheng Huang   +14 more
doaj   +1 more source

A multifaceted microenvironment nanoregulator for targeted ovarian cancer therapy

open access: yesFrontiers in Pharmacology
The treatment of ovarian cancer is hindered by its insidious onset and rapid progression. Exosomes (EXOs) present a promising therapeutic strategy for ovarian cancer by modulating the tumor microenvironment.
Yizheng Zu   +15 more
doaj   +1 more source

[New strategies for fertility preservation in young women with cancer]

open access: yes, 2009
Especially young women with cancer face rising survival rates due to remarkable progress in oncologic therapies. Preserving fertility is a major concern for both patients and their next of kin.
von Wolff, Michael   +2 more
core  

Fertility preservation in cancer patients

open access: yes, 2018
Introduction. Progress in the field of cancer treatment has led to increased survival rate of cancer patients. Chemotherapy and surgical treatment may be the consequence of decreased fertility in both genders. Fertility Preservation. Some of the
Aleksandra Trninic-Pjevic   +3 more
core   +1 more source

8th World Congress of International Society for Fertility Preservation (ISFP)

open access: yes
Fertility preservation in young patients with Turner ...
Dolmans, Marie-Madeleine   +1 more
core  

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