Results 61 to 70 of about 31,457 (267)

Pubertal low dose exposure to benzophenone-3 (BP-3) alters murine mammary stem cell functions

Ecotoxicology and Environmental Safety
Benzophenone-3 (BP-3) is an organic UV filter that is widely used in personal care products and has been indicated to have negative impacts on the environment and human health.
Hui Gao, Xintong Yang, Pengge Pan, Xueli Liu, Yan Ma, Yadan Chen, Yunxin Liu, Yaqi Sun, Sinan Cao, Yuan Tian, Yanzhou Yang   +10 more
doaj   +1 more source

SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer

Advanced Science, EarlyView.
Elevated levels of the plasticizer DEHP associate with earlier breast cancer diagnosis. DEHP enhances glutamine‐powered energy production via the transporter SLC6A14 and pushes mitochondria toward fusion, driving tumor initiation by boosting cancer stemness. Blocking SLC6A14 lowers stemness, slows tumors, and improves chemotherapy response.
Dai‐Wei Hu, Chih‐Hao Huang, Yu‐Hao He, Ya‐Ling Wei, Shu‐Wei Hu, Fang‐Ju Cheng, Thanh Kieu Huynh, Bo‐Rong Chen, Bo‐Wei Wang, Li‐Chi Kuan, Der‐Yen Lee, Ming‐Hsin Yeh, Ya‐Jen Chang, Liang‐Chih Liu, Mien‐Chie Hung, Wei‐Chien Huang   +15 more
wiley   +1 more source

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

Advanced Science, EarlyView.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park, Min‐Ji Kim, Jae‐Ho Shin, Eunsoo Kim, Myeongjoo Son, Seungjun Lee   +5 more
wiley   +1 more source

Comparative effects of streptozotocin, dehydroepiandrosterone and letrozole with high fat diet on ovarian injury induction and functional impairment

Scientific Reports
This study investigates the mechanisms by which environmental factors affect ovarian function. Environmental toxins and unhealthy lifestyles adversely affect women’s health, primarily impair ovarian function. Environmental toxins and unhealthy lifestyles
Leyi Yu, Qingjie Peng, Cunling Ma, Jiahui Ouyang, Hongru Ma, Shuzhe Fan, Miao Sun, Huiming Ma, Xiaoli Du, Xiangdong Zhu, Guangyong Li, Rui He   +11 more
doaj   +1 more source

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

Advanced Science, EarlyView.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun, Lifa Zhu, Yutong Li, Jinyan Tang, Tao Zhang, Hengjia Zhang, Wanchu Wang, Lufan Li, Shuhui Bian, Xin Wu   +9 more
wiley   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

Advanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li, Yuge Chen, Dongdong Tang, Yuying Sheng, Xu Han, Hao Geng, Na Zhang, Zongliu Duan, Guanxiong Wang, Yang Gao, Rui Guo, Rong Hua, Zhiming Ding, Chuan Xu, Qunshan Shen, Zhen Yu, Bing Song, Mingrong Lv, Yuping Xu, Huan Wu, Ji Wu, Yunxia Cao, Xiaojin He   +22 more
wiley   +1 more source

578 The impact of tumor size on oncological outcomes of fertility preservation surgery in early cervical cancer: a multi-centric study by Spain- GOG [PDF]

, 2021
Blanca Gil Ibáñez, Aureli Torné, Antonio Gil‐Moreno, A. Martín, Gemma Mancebo, Pluvio Coronado, MT Marina Martín, Antoni Llueca, Berta Díaz‐Feijoó, A. Tejerizo-García   +9 more
openalex   +1 more source

Amphiphilic Polymer Conetworks for Non‐Fullerene Organic Solar Cells: Regulated Molecular Stacking Enables Efficient Downconversion

Advanced Energy Materials, EarlyView.
This work presents a novel bulk‐heterojunction‐integrated organic luminophore geometry using amphiphilic polymer conetworks as an interlayer scaffold. The design enhances optoelectronic performance via efficient downconversion and reinforced molecular stacking, offering a versatile architecture that paves the way for next‐generation organic solar cells.
Chieh‐Szu Huang, Danbi Kim, Wenyan Yang, Yang Lu, Robert J. E. Westbrook, Huagui Lai, Zimu Wei, Chaeyeon Lee, Fan Fu, Neil C. Greenham, Bo Ram Lee, Samuel D. Stranks   +11 more
wiley   +1 more source

FERTILITY PRESERVATION: Construction and use of artificial ovaries [PDF]

, 2019
Marie‐Madeleine Dolmans, Christiani A. Amorim   +1 more
openalex   +1 more source

Wine Tourism as a Catalyst for Sustainable Performance: The Mediating Role of Corporate Legitimacy and Green Innovation

Agribusiness, EarlyView.
ABSTRACT This study aims to explore the influence of Wine Tourism (WT) on the Sustainable Performance (SP) of wineries in Spain. It particularly investigates how Corporate Social Legitimacy (CSL) and Green Innovation (GI) may act as intermediary factors in this relationship.
Javier Martínez‐Falcó, Eduardo Sánchez‐García, Bartolomé Marco‐Lajara, Luis A. Millán‐Tudela   +3 more
wiley   +1 more source