Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum +4 more
wiley +1 more source
Sperm DNA fragmentation and its impact on pregnancy outcomes: a narrative review focusing on threshold definition and clinical strategies. [PDF]
Cheng S +10 more
europepmc +1 more source
ABSTRACT Objective To characterize the overall diagnostic yield of sequential chromosomal microarray (CMA) and exome sequencing (ES) across the phenotypic spectrum of fetal growth restriction (FGR). Methods A retrospective cohort of 320 consecutive FGR pregnancies presenting at ≥ 20 weeks to a tertiary fetal medicine unit (2020–2025).
Hadas Miremberg +11 more
wiley +1 more source
Calcium ionophore supplementation for immature oocytes and pentoxifylline supplementation for immotile sperms: A study of embryo quality of difficult cases in <i>in vitro</i> fertilization in a mouse model. [PDF]
Wasian GR +5 more
europepmc +1 more source
Climate change is intensifying heat, drought, and food insecurity, threatening dryland farming and carbon management worldwide. We reviewed research on sorghum, a drought‐adapted C4 crop, covering physiology, roots, biomass allocation, soil carbon, bioenergy, breeding, phenotyping, management, and policy.
Monir Idres Yahya Ahmed +4 more
wiley +1 more source
Sperm surface protein disulfide isomerase ERp57 is crucial for mammalian fertilization but functions independently of IZUMO1. [PDF]
Forster E +8 more
europepmc +1 more source
Genome editing technologies such as CRISPR‐Cas are reshaping debates about the future of agriculture, yet disagreement over how these crops should be regulated remains widespread. This study clarifies the range of arguments used in scientific discussions about genome‐edited crops, making underlying assumptions and value judgements more visible.
Philippe Mathys +3 more
wiley +1 more source
Perivitelline space volume and embryonic outcomes in conventional IVF: a single-center retrospective study with mixed-effects model analysis. [PDF]
Wang X +6 more
europepmc +1 more source
Impact of intimate partner violence on <i>in vitro</i> fertilization outcomes among infertile women: a retrospective cohort study. [PDF]
Wang X +9 more
europepmc +1 more source
Correction: Overcoming oral medication allergy and cervical stenosis in an anovulatory in vitro fertilization patient: a case report. [PDF]
Dmitrovic R +4 more
europepmc +1 more source

