Results 91 to 100 of about 1,787,060 (299)

Editorial: Women in developmental and reproductive toxicology: 2021

Frontiers in Toxicology, 2022
Jennifer J. Adibi, Sofie Christiansen, Suzanne E. Fenton, Alison Holloway, Heather B. Patisaul   +4 more
doaj   +1 more source

Effect of phenylephrine vs. ephedrine on frontal lobe oxygenation during caesarean section with spinal anaesthesia: An open label randomised controlled trial

Frontiers in Physiology, 2014
Background: During caesarean section spinal anaesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine.
Visti Torbjørn Foss, Kim Zillo Rokamp, Robin Daniel Christensen, Peter eNissen, Niels Henry Secher, Henning Bay Nielsen   +5 more
doaj   +1 more source

Autopsy after termination of pregnancy for fetal anomaly: retrospective cohort study [PDF]

, 2004
P A Boyd
openalex   +1 more source

An automated framework for image classification and segmentation of fetal ultrasound images for gestational age estimation

, 2021
Juan Carlos Prieto, Hina Shah, Alan J. Rosenbaum, Xiaoning Jiang, Patrick Musonda, Joan T. Price, Elizabeth M. Stringer, Bellington Vwalika, David M. Stamilio, Jeffrey S. A. Stringer   +9 more
openalex   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Prenatal Diagnosis of Congenital Dermal Sinus

American Journal of Perinatology Reports, 2015
Background Congenital dermal sinus (CDS) is an uncommon form of spinal dysraphism. Although postdelivery identification in the neonate is aided by several associated physical examination findings, establishing this diagnosis prenatally has proven to be ...
Sharif Sakr, Yedathore Mohan, Asif Malik, Ghaus Malik, Bernard Gonik   +4 more
doaj   +1 more source

Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

Journal of Neuroscience, 2007
Schizophrenia and autism are thought to result from the interaction between a susceptibility genotype and environmental risk factors. The offspring of women who experience infection while pregnant have an increased risk for these disorders.
Stephen E P Smith, Jennifer Li, K. Garbett, K. Mirnics, P. Patterson   +4 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source