Results 111 to 120 of about 3,131,553 (238)

Influence of 6‐Trifluoromethyluracil Versus Chloride Counterions in the Properties of Bis‐(1,10‐Phenanthroline)chloridecopper(II) Motif: Spectroscopic and In Vitro Biological Activity Assays

European Journal of Inorganic Chemistry, EarlyView.
This work explores the influence of 6‐trifluoromethyluracil versus chloride counterions on the antibacterial and antitumoral activities of bis‐(1,10‐phenanthroline)chloridecopper(II) motif. The counterion modulates antibacterial potency and the identity of the dominant reactive species, while leaving DNA recognition by the shared cation essentially ...
Francisco Mastrobuono‐Cordeiro, Gabriele de M. Pereira, Douglas H. Nakahata, Stefano Scoditti, Fernanda V. P. de V. Azevedo, Letícia P. de Oliveira, Silmara C. L. Frajácomo, Javier Ellena, Pedro H. de O. Santiago, Daniel Reta, Gilberto C. Franchi, Wilton R. Lustri, Carmen S. P. Lima, Pedro P. Corbi, Raphael E. F. de Paiva   +14 more
wiley   +1 more source

Highly conductive and robust epidermal dry electrode for long‐term interval biopotential monitoring

FlexMat, EarlyView.
A freestanding PVA‐PBFDO conductive dry electrode combines high conductivity, flexibility, and environmental stability to enable long‐term, high‐fidelity electrophysiological (EP) signal monitoring. Its patterning capability further facilitates the fabrication of wearable and multi‐channel bioelectronic devices.
Anni Sun, Tenglong Luo, Huanxin Su, Zhengyan He, Fuchun Nan, Shuo Wang, Yu Wang, Yuanhao Wu, Lingyun Wang, Jie Zhang, William W. Yu   +10 more
wiley   +1 more source

Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization

iMetaOmics, EarlyView.
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao, Hang You, Zongyi Liu, Yong Sun, Yu Zhang, Li Wei, Ning Ling, Hong Ren, Shiying Li, Peng Hu, Mingli Peng   +10 more
wiley   +1 more source

Family and friends perspectives on communication barriers and patient social isolation in Canadian hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Hospitalization can disrupt patients’ communication and social connections, potentially contributing to social isolation, while the supportive role of family and friends in communication is often underrecognized. Objective This study examines communication access barriers and their association with social isolation among ...
Sama Amirkhani‐Ardeh, Sasha Wade, Emma Rossnagel, Aderonke Agboji, Davina Banner, Trina Fyfe, Tammy Klassen‐Ross, Shannon Freeman   +7 more
wiley   +1 more source

Screening approaches for detecting fetal alcohol spectrum disorder in children, adolescents, and adults: A systematic review [PDF]

, 2020
Identification of fetal alcohol spectrum disorder (FASD) may help facilitate the provision of supports and services for those who need them. Screening has been proposed as an important step in recognizing those at risk of having FASD.
Grubb, Melissa
core  

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Mechanisms of influence: Alcohol industry submissions to the inquiry into fetal alcohol spectrum disorders

, 2016
Mechanisms of influence: Alcohol industry submissions to the inquiry into fetal alcohol spectrum ...
A Ferguson (7801841), Florentine Martino (13083402), MR Avery (14465046), C Giorgi (13626322), Kerri Coomber (13064904), N Droste (9891362), Peter Miller (13089540)   +6 more
core  

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source