Results 51 to 60 of about 2,983,769 (289)
Advanced Science, EarlyView.A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal +5 more
wiley +1 more source
The Influence of FASD on Psychiatric Disorders
Journal of Education, Health and SportThe Fetal Alcohol Spectrum Disorders (FASD) encompass a variety of physical, behavioral and neurological disorders resulting from fetal alcohol exposure.
Alicja Staszek +9 more
doaj +1 more source
Intelligence and fetal alcohol spectrum disorders
Journal of Population Therapeutics and Clinical Pharmacology, 2017 Background The studies on intelligence in individuals with fetal alcohol exposure are conflicting. Some have found a relevant impairment in this population, while others found results that were consistent with the population at large. Objectives Describe the results of studies on intelligence in individuals with Fetal Alcohol Spectrum
Vanessa K de L, Ferreira +1 more
openaire +3 more sources
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Challenges in assessing young children for fetal alcohol spectrum disorder and a proposed solution
, 2021 Introduction: Current diagnostic assessment for fetal alcohol spectrum disorder (FASD) is time and resource intensive. And further complicated by the paucity of neuropsychological instruments designed and normed for young children.
Eggins, Elizabeth +9 more
core +1 more source
Advanced Science, EarlyView.The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang +12 more
wiley +1 more source
Advanced Science, EarlyView.Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie +12 more
wiley +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
ChildrenFetal alcohol spectrum disorder (FASD) is commonly misdiagnosed because of the complexity of presentation and multiple diagnostic criteria. FASD includes four categorical entities (fetal alcohol syndrome, partial fetal alcohol syndrome, alcohol related ...
Lorel Breuer +2 more
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2009 OBJECTIVE: To analyze the metabolic constitution of brain areas through proton magnetic resonance spectroscopy in children affected with fetal alcohol spectrum disorder compared with normal children. METHOD: The sample of this case-control study included
Rita de Cássia Ferreira Gonçalves +7 more
doaj +1 more source