Results 71 to 80 of about 3,131,553 (238)

Prevention of Fetal Alcohol Spectrum Disorder: Current Canadian Efforts and Analysis of Gaps

, 2016
Effective prevention of risky alcohol use in pregnancy involves much more than providing information about the risk of potential birth defects and developmental disabilities in children. To categorize the breadth of possible initiatives, Canadian experts
Rose A. Schmidt, Natalie Hemsing, Nancy Poole, Courtney Green   +3 more
core   +1 more source

Yarning about fetal alcohol spectrum disorder: outcomes of a community-based workshop

, 2020
Introduction: There is a lack of neurodevelopmental assessment services in rural and remote locations in Australia that consider fetal alcohol spectrum disorder as a possible outcome.Methods: Eighty-seven participants attended a workshop to support ...
Wood, Andrew, Webster, Heidi, Morrissey, Shirley, Shanley, Dianne, Liu, Wei, O'Callaghan, Frances, Page, Marjad, Hawkins, Erinn, O’Callaghan, Frances, Reid, Natasha, Katsikitis, Mary, Shelton, Doug, Shirley Morrissey, Doug Shelton, Heidi Webster, Erinn Hawkins, Mary Katsikitis, Frances O’Callaghan, Dianne Shanley, Andrew Wood, Wei Liu, Marjad Page, Natasha Reid   +22 more
core   +1 more source

CaMKIIδ Phosphorylates AUP1 to Promote Pancreatic Tissue Repair and Acinar‐to‐Ductal Metaplasia Formation via Mediating PERK‐Dependent Unfolded Protein Responses

Advanced Science, EarlyView.
CaMKIIδ–AUP1 signaling maintains PERK‐dependent ER homeostasis during ADM‐mediated pancreatic repair. ABSTRACT Pancreatic repair after acute pancreatitis (AP) is essential for restoring tissue integrity, but the intrinsic mechanisms coordinating acinar plasticity and regeneration remain poorly understood.
Yonghao Chen, Ziying Han, Zihan Yang, Jie Wu, Kaixin Peng, Xiuli Zhang, Bintao Qiu, Jianqiang Wu, Xiaomin Hu, Dong Wu, Li Wen   +10 more
wiley   +1 more source

‘I don't know what is autism, what is normal teenage behaviour, and what is naughtiness’: Conceptualising child and adolescent to parent violence in the context of neurodevelopmental difference

Children &Society, EarlyView., 2023
Abstract This article presents findings from a UK‐based qualitative study that explored parents/carers experiences of child to parent violence (CPV) from their child who has a neurodevelopmental difference. The study used semi‐structured interviews with 15 mothers who were experiencing physical and psychological violence from their child, often on a ...
Amanda Holt
wiley   +1 more source

Fetal Alcohol Spectrum Disorder [PDF]

, 2019
Fetal Alcohol Spectrum Disorder (FASD) is a devastating disorder and is predicted more common than once thought. Recent research shows that the prevalence of Fetal Alcohol Spectrum Disorder is between 1% and %5 of the population, making it possibly more ...
Jordan, Teresa
core  

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

Prenatal Alcohol Use and Fetal Alcohol Spectrum Disorder in Indiana

, 2012
Consumption of alcohol during pregnancy can cause the infant to be born with a fetal alcohol spectrum disorder (FASD). FASD is not a diagnosis, but an umbrella term that describes a group of conditions associated with prenatal alcohol exposure, including
Greene, Marion
core   +1 more source

Profile of children diagnosed with a fetal alcohol spectrum disorder: a retrospective chart review [PDF]

, 2017
Introduction and Aims. Fetal alcohol spectrum disorder (FASD) is a significant public health concern, and growing recognition in Australia led to the establishment of a specialist service for young children.
Warner, Judith, Doug Shelton, Judith Warner, Frances O'Callaghan, O'Callaghan, Frances, Sharon Dawe, Reid, Natasha, Dawe, Sharon, Natasha Reid, Shelton, Doug   +9 more
core   +1 more source

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen, Xiaoxiao Chen, Baozhu Yang, Hui Xu, Xueting Sun, Hongkai Qi, Huilin Hu, Ronghua Wu, Fengkai Qiu, Bing Wu, Yu Luo, Gaofeng Shu, Jiansong Ji   +12 more
wiley   +1 more source

Fetal alcohol spectrum disorder: A global perspective seeing the unseen: Fetal alcohol spectrum disorder (s) in child welfare service provision. A discussion paper

Child Protection and Practice
Children involved in child welfare systems frequently experience complex and overlapping biopsychosocial adversities, including neurodevelopmental impairments associated with prenatal alcohol exposure (PAE) and Fetal Alcohol Spectrum Disorder (FASD ...
William Curran
doaj   +1 more source