Results 21 to 30 of about 2,021,787 (280)

Decoding neurodevelopment risks of exposures to intoxication, infection, and trauma during pregnancy. [PDF]

Pregnancy (Hoboken)
Abstract The maternal environment plays a pivotal role in fetal neurodevelopment, but adverse conditions during pregnancy may disrupt key developmental processes. Conditions such as intoxication, infection, or trauma during pregnancy have been associated with impaired fetal oxygenation, altered immune signaling, and disrupted placental function, which ...
Lujan BE, Giordano KR, Gonzalez-Ricon RJ, Giblin OC, Manriquez M, Qiu S, Antonson AM, Lifshitz J.   +7 more
europepmc   +2 more sources

Fetal alcohol spectrum disorder among pre-adopted and foster children

BMC Pediatrics, 2020
Background Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disorders. Children in foster care or domestically adopted are at greater risk for FASD.
Ariel Tenenbaum, Asaf Mandel, Talia Dor, Alon Sapir, Orly Sapir-Bodnaro, Pnina Hertz, Isaiah D. Wexler   +6 more
doaj   +1 more source

Fetal Alcohol Spectrum Disorders and Inadequacy of Care: Importance of Raising Awareness in Clinical Practice

Children, 2023
Prenatal alcohol exposure is one of the major avoidable causes of developmental disruption and health abnormalities in children. Fetal alcohol spectrum disorders (FASDs), a significant consequence of prenatal alcohol exposure, have gained more attention ...
Sigita Lesinskienė, Emilijus Žilinskas, Algirdas Utkus, Rūta Marčiukaitytė, Gabrielė Vasiliauskaitė, Rugilė Stankevičiūtė, Odeta Kinčinienė   +6 more
doaj   +1 more source

Embryonic ethanol exposure on zebrafish early development

Brain and Behavior, 2021
Introduction Embryonic exposure to ethanol leads to a condition of physical, behavioral, and cognitive deficiencies named fetal alcohol spectrum disorders (FASD). The most severe variations are in fetal alcohol syndrome (FAS), which is easier to diagnose
Jaquelinne Pinheiro‐da‐Silva, Ana Carolina Luchiari   +1 more
doaj   +1 more source

Homozygous mutation in the ADH6 gene, involved in alcohol metabolism, associated with a multisystem disorder, analogous to the fetal alcohol syndrome

Journal of Clinical and Translational Endocrinology Case Reports, 2023
Introduction: In humans, there is considerable individual variability in ethanol metabolism, and these differences have been partially attributed to genetic variability at the ADH locus at 4q22-23, where seven genes are found.
Ahmed Bouhouche, Omar Askander, Hicham Charoute, Mouna Sabib, Abdeljalil El Quessar, Amine El Hassani, Naima Erreimi   +6 more
doaj   +1 more source

Parietal dysfunction during number processing in children with fetal alcohol spectrum disorders

NeuroImage: Clinical, 2015
Number processing deficits are frequently seen in children prenatally exposed to alcohol. Although the parietal lobe, which is known to mediate several key aspects of number processing, has been shown to be structurally impaired in fetal alcohol spectrum
K.J. Woods, E.M. Meintjes, C.D. Molteno, S.W. Jacobson, J.L. Jacobson   +4 more
doaj   +1 more source

Sleep problems among children with Fetal Alcohol Spectrum Disorders (FASD)- an explorative study

Italian Journal of Pediatrics, 2021
Background Fetal alcohol spectrum disorders (FASD) is a group of conditions resulting from prenatal alcohol exposure (PAE). Patients with FASD experience a variety of neuropsychological symptoms resulting from central nervous system impairment. Little is
Katarzyna Anna Dylag, Bożena Bando, Zbigniew Baran, Paulina Dumnicka, Katarzyna Kowalska, Paulina Kulaga, Katarzyna Przybyszewska, Jakub Radlinski, Sylvia Roozen, Leopold Curfs   +9 more
doaj   +1 more source

Fetal Alcohol Spectrum Disorder Prevalence Studies in School Settings: A Global Systematic Review of Methods, Measures, Strengths and Limitations. [PDF]

Drug Alcohol Rev
ABSTRACT Issues Fetal alcohol spectrum disorder (FASD) is a prevalent yet widely underdiagnosed neurodevelopmental condition resulting from prenatal alcohol exposure (PAE). FASD has profound lifelong implications for affected individuals, their caregivers and society.
McCarthy R, Pink J, Olivier L, Gilbert D, Mukherjee R, Cook PA.   +5 more
europepmc   +2 more sources

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Aggressive behavior in adolescents with fetal alcohol spectrum disorders [PDF]

, 2013
Includes bibliographical references.Behavioral studies of fetal alcohol spectrum disorders (FASD) have indicated that aggression is common amongst alcohol-exposed adolescents, and that it appears to become more prevalent with age in that population. Such
Smith, Keelie
core   +1 more source