Results 51 to 60 of about 645,177 (249)

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Assessment Of Fetal Outcome In Women Undergoing Emergency Caesarean Section For Fetal Distress In Tertiary Care Hospital

Journal of Rawalpindi Medical College
Objective: This study aims to assess the fetal outcome in terms of early neonatal mortality among women undergoing emergency caesarean section for fetal distress.
Noor Fatima, Khansa Iqbal, Amna Abbasi, Nabeela Waheed, Amara Arooj, Maliha Sadaf   +5 more
doaj   +1 more source

Ultrasonic character istics and clinical significance of umbilical cord blood flow in acute fetal distress

Journal of Acute Disease, 2016
Objective: To study ultrasonic characteristics of umbilical cord blood flow in acute fetal distress and its correlation with umbilical artery blood gas parameters, oxidative stress parameters, neonatal brain injury and myocardial injury.
Wei Dai, Yin Xu, Xing-Wei Ma, Li Zhang, Ming-Juan Zhu   +3 more
doaj   +1 more source

Diagnosis of fetal distress

, 2012
Fetal distress is a very broad term, which can be used in many clinical situations. Although it is difficult to give a precise clinical definition, obstetricians usually use this term to indicate that the fetus is becoming hypoxic. Immediate delivery has
Felice Petraglia, Boni, Carlotta, Carlotta Boni, Filiberto M. Severi, Petraglia, Felice, Norman, Jane, Severi, Filiberto M., Jane Norman   +7 more
core   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

Prenatal Prediction of Fetal Lung Maturity Using 3D Lung Volume, Lung-to-Liver Intensity Ratio Tissue Histogram and Pulmonary Artery Doppler Indices [PDF]

International Journal of Medical Arts
Background: Fetal lung maturity assessment is regarded as the most critical factor for identifying the optimal delivery time. A noninvasive sonographic technique is necessary to evaluate fetal lung development, as amniocentesis is an invasive method that
Aml Omar, Ahmed Tharwat, Mohamed Aboelnasr, Haytham Hamza, Shaimaa Hassanein, Wael Eldamaty   +5 more
doaj   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Women's experience of coping with termination of pregnancy for fetal abnormality: coping strategies, perinatal grief and posttraumatic growth [PDF]

Pregnancy termination for fetal abnormality (TFA) represents 2% of all terminations in England and Wales. In recent years, the number of TFAs has risen (3,099 in 2014 compared to 2,085 in 2009) due to technological developments in prenatal diagnosis and ...
Lafarge, Caroline
core   +3 more sources

Tocolytics for suspected intrapartum fetal distress.

, 2000
BACKGROUND Prophylactic tocolysis with betamimetics and other agents has become widespread as a treatment for fetal distress. Uterine relaxation may improve placental blood flow and therefore fetal oxygenation.
Kulier R, Hofmeyr GJ
core   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source