Results 61 to 70 of about 72,689 (257)

Pathogenetic role of vitamin D deficiency and immune-inflammatory disorders in development of fetal distress in pregnant women with chronic hydramnion

open access: yesZaporožskij Medicinskij Žurnal, 2019
The role of vitamin D deficiency and immune-inflammatory disorders in the mechanisms of fetal distress development in pregnant women with chronic polyhydramnios remains unstudied.
N. A. Haistruk   +4 more
doaj   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang   +12 more
wiley   +1 more source

Doppler Assessment of Fetal Lung: Where do we stand

open access: yesArcades of Medicine
Accurate prenatal assessment of fetal lung development is essential for predicting neonatal respiratory outcomes and guiding the management of high-risk pregnancies.
Mohamed Rezk
doaj   +1 more source

Fetal heart rate abnormalities during and after external cephalic version: Which fetuses are at risk and how are they delivered?

open access: yesBMC Pregnancy and Childbirth, 2017
Background Fetal heart rate abnormalities (FHR) during and after external cephalic version (ECV) are relatively frequent. They may raise concern about fetal wellbeing. Only occasionally they may lead to an emergency cesarean section.
Simone M. Kuppens   +4 more
doaj   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Fetal electronic monitoring and cesarean section rate

open access: yesPayesh, 2012
Objective (s): To investigate whether the use of fetal monitoring had an effect on cesarean section rate at Mahdieh hospital.Methods: This retrospective, analytical cross sectional study involved patients' data from deliveries occurring at Mahdieh ...
Leila Hadipoor Jahromi   +2 more
doaj  

Avaliação do bem estar fetal intraparto.

open access: yesActa Médica Portuguesa, 2001
Nowadays the intrapartum assessment of fetal well-being and obstetric intervention during labor demand careful clinical examination and the knowledge of techniques such as cardiotocography, amnioinfusion, fetal scalp blood sampling and ultrasonography ...
M J Carinhas
doaj   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

open access: yesAdvanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma   +14 more
wiley   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

open access: yesAdvanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao   +11 more
wiley   +1 more source

CAUSES OF ADVERSE FETAL AND NEONATAL OUTCOMES IN PATIENTS WITH SEVERE PREECLAMPSIA AND /OR HYPOTROPHIC FETAL DISTRESS

open access: yesМать и дитя в Кузбассе, 2020
Aim – to determine the causes of unfavorable outcomes for fetuses and newborns in patients with severe preeclampsia and/or hypotrophic fetal distress.
Елена Станиславовна Кравцова   +3 more
doaj  

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