Results 51 to 60 of about 266,924 (341)

Digynic triploidy: Utility and challenges of noninvasive prenatal testing [PDF]

, 2015
Low fraction fetal DNA in noninvasive prenatal testing in the context of fetal growth restriction and multiple congenital anomalies should alert medical professionals to the possibility of digynic triploidy.
Baldridge, Dustin, Cottrell, Catherine E, Fleischer, Julie, Goetzinger, Katherine, Shenoy, Archana, Shinawi, Marwan, White, Frances V   +6 more
core   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

IJCM_77A: Predictors of fetal growth restriction in preterm birth

Indian Journal of Community Medicine
Background: Fetal growth restriction (FGR) is defined as fetuses whose estimated fetal weight or abdominal circumference is below the 10th percentile for gestational age.
Ganesh, Suchetha S Rao, Prasanna Mithra, Santosh Rai, Keshava K Pai, Shraddha K Shetty, Sauda, K M Akshaya   +7 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Role of uteroplacental and fetal Doppler in identifying fetal growth restriction at term. [PDF]

, 2017
Identification of the fetus at risk of adverse outcome at term is a challenge to both clinicians and researchers alike. Despite the fact that fetal growth restriction (FGR) is a known risk factor for stillbirth, at least two thirds of the stillbirth ...
Altman, American College of Obstetricians and Gynecologists, Arduini, Asma Khalil, Bakalis, Baschat, Basky Thilaganathan, Battaglia, Bellido-González, Bernardes, Bukowski, Chang, Cruz-Martinez, de Jong, DeVore, Ebbing, Egaña-Ugrinovic, Eixarch, Figueras, Figueras, Flood, Francis, Gardosi, Gardosi, Gardosi, Gardosi, Gardosi, Ghosh, Gomez-Roig, Gordijn, Gramellini, Hepburn, Hershkovitz, Hutcheon, Hutcheon, Karlsen, Kean, Khalil, Khalil, Khalil, Khalil, Lai, Lai, Lindqvist, Maulik, McIntyre, Melchiorre, Melchiorre, Moraitis, Morales-Roselló, Morales-Roselló, Morken, Nassr, Pallotto, Papageorghiou, Pasupathy, Pilliod, Plasencia, Poon, Prior, Regan, Romero, Royal College of Obstetricians and Gynaecologists, Royston, Royston, Severi, Singh, Sovio, Sterne, Stock, Valiño, Vasak, Vergani, Yu, Zhang   +74 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Maternal inflammation at 0.7 gestation in ewes leads to intrauterine growth restriction and impaired glucose metabolism in offspring at 30 d of age [PDF]

, 2019
Fetal programming associated with intrauterine growth restriction (IUGR) leads to lifelong deficits in growth and metabolic function (Hales and Barker, 2013).
Beard, Joslyn K., Beede, Kristin A., Cadaret, Caitlin N., Gibbs, Rachel L., Petersen, Jessica L., Posont, Robert J., Swanson, Rebecca M., Yates, Dustin T.   +7 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Placental Malaria: From Infection to Malfunction [PDF]

, 2006
Malaria during pregnancy is a major factor in infant morbidity and mortality. In this issue of Cell Host and Microbe, Conroy et al. (2013) propose that C5a, a product of complement cascade activation, counteracts the placental vascular remodeling ...
Luciana Vieira de Moraes, Carlos Penha-Gonçalves, Avery, Conroy, Conroy, Duffy, Girardi, Head, Lucchi, Moraes, Rodrigues-Duarte, Salanti   +11 more
core   +1 more source

Angiogenic factors for planning fetal surveillance in fetal growth restriction and small‐for‐gestational‐age fetuses: A prospective observational study [PDF]

, 2022
Erika Bonacina, Manel Mendoza, Alba Farràs, Pablo García‐Manau, Berta Serrano, Ivan Hurtado, Raquel Ferrer‐Oliveras, Lidia Illan, Mireia Armengol‐Alsina, E. Carreras   +9 more
openalex   +1 more source