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Congenital heart diseases are considered the most common fetal anomalies. While some of these anomalies may have a minimal impact on the life of a newborn, some may result in neonatal deaths in the early period.
Barış Sever, Halil Gürsoy Pala
doaj +2 more sources
Fetal Heart Rate Fragmentation [PDF]
Intrapartum fetal monitoring's primary goal is to avoid adverse perinatal outcomes related to hypoxia/acidosis without increasing unnecessary interventions. Recently, a set of indices were proposed as new biomarkers to analyze heart rate (HR), termed HR fragmentation (HRF). In this work, the HRF indices were applied to intrapartum fetal heart rate (FHR)
Matilde Costa +6 more
openaire +3 more sources
Genetic aetiology distribution of 398 foetuses with congenital heart disease in the prenatal setting
Aims Copy number variant‐sequencing (CNV‐seq) and exome sequencing (ES) have been used as powerful tools in understanding the role of genetic variants in congenital heart diseases (CHDs).
Tong Yi +11 more
doaj +1 more source
Placental DNA Methylation Abnormalities in Prenatal Conotruncal Heart Defects
Objective: This study aims to characterize the abnormal changes in placental DNA methylation associated with conotruncal heart defects (CTDs) and the level of methylation as epigenetic biomarkers for CTDs detection.Methods: This was a prospective study ...
Jingjing Liu +17 more
doaj +1 more source
Genetics and Clinical Features of Noncompaction Cardiomyopathy in the Fetal Population
Objectives: Noncompaction Cardiomyopathy (NCCM) has been classified as primary genetic cardiomyopathy and has gained increasing clinical awareness; however, little is known about NCCM in the fetal population.
Hairui Sun +27 more
doaj +1 more source
Total anomalous pulmonary venous connection (TAPVC) is a rare congenital cardiac malformation, and prenatal detection of TAPVC malformation remains a challenging. TAPVC can be easily missed or misdiagnosed in prenatal examinations.
Jiaqi Zhang +7 more
doaj +1 more source
Optimization of a Third-Order Gradiometer for Operation in Unshielded Environments [PDF]
The optimum geometry of a third-order gradiometer for operation in unshielded environments is discussed. The optimization result depends on the specific signal and noise conditions. The fetal heart is considered as an example of the signal source.
Brake, H.J.M. ter +3 more
core +9 more sources
Generation of a TIMP3 knockout stem cell line via CRISPR/Cas9 system
The tissue inhibitors of metalloproteinases 3 (TIMP3) play an essential role in the tumorigenesis of human pancreatic endocrine tumors and Sorsby fundus dystrophy. To further investigate the significance of TIMP3 in disease, we used CRISPR/Cas9 to create
Tong Yi +4 more
doaj +1 more source
Background The uterine cervix is a mechanical and immunological barrier against ascending infection during pregnancy. Cervical insufficiency (CI), a painless cervical dilation that occurs in the mid-trimester, is an important cause of extremely preterm ...
Ga-Hyun Son +7 more
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ObjectivesTo analyze the clinical characteristics, echocardiographic features, and prognosis of fetuses based on three groups of cardiac manifestations associated with maternal anti-Ro and anti-La antibodies in China.
Xin Wang +10 more
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