Results 61 to 70 of about 922,524 (371)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Novel hybrid extraction systems for fetal heart rate variability monitoring based on non-invasive fetal electrocardiogram [PDF]

open access: yes, 2019
This study focuses on the design, implementation and subsequent verification of a new type of hybrid extraction system for noninvasive fetal electrocardiogram (NI-fECG) processing.
Jaroš, René   +3 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Comparison of Machine Learning Techniques for Fetal Heart Rate Classification

open access: yes, 2017
Cardiotocography is a monitoring technique providing important and vital information on fetal status during antepartum and intrapartum periods. The advances in modern obstetric practice allowed many robust and reliable machine learning techniques to be ...
Zafer Cömert, A. F. Kocamaz
semanticscholar   +1 more source

Passive fetal heart rate monitoring apparatus and method with enhanced fetal heart beat discrimination [PDF]

open access: yes, 1996
An apparatus for acquiring signals emitted by a fetus, identifying fetal heart beats and determining a fetal heart rate. Multiple sensor signals are outputted by a passive fetal heart rate monitoring sensor.
Livingston, David L.   +2 more
core   +1 more source

Amélioration de l'estimation du rythme cardiaque foetal en utilisant les signaux Doppler directionnels et YIN [PDF]

open access: yes, 2012
National audienceTechniques dedicated to the fetal heart rate detection identify the patterns that repeat themselves over the time. The heart rate estimation is algorithmically similar to the estimation of the fundamental frequency (pitch) of voice ...
Girault, Jean-Marc   +2 more
core   +3 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Perceptions and experiences of skilled birth attendants on using a newly developed strap-on electronic fetal heart rate monitor in Tanzania

open access: yesBMC Pregnancy and Childbirth, 2019
Background Regular fetal heart rate monitoring during labor can drastically reduce fresh stillbirths and neonatal mortality through early detection and management of fetal distress. Fetal monitoring in low-resource settings is often inadequate.
Sara Rivenes Lafontan   +4 more
doaj   +1 more source

Investigating pH based evaluation of fetal heart rate (FHR) recordings

open access: yesHealth technology, 2017
Cardiotocography (CTG) is a standard tool for the assessment of fetal well-being during pregnancy and delivery. However, its interpretation is associated with high inter- and intra-observer variability.
G. Georgoulas   +5 more
semanticscholar   +1 more source

Mathematical tools for identifying the fetal response to physical exercise during pregnancy [PDF]

open access: yes, 2008
In the applied mathematics literature there exist a significant number of tools that can reveal the interaction between mother and fetus during rest and also during and after exercise.
Barakat Carballo, Ruben   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy