Results 91 to 100 of about 821,341 (299)

Haptoglobin Phenotype, Preeclampsia Risk and the Efficacy of Vitamin C and E Supplementation to Prevent Preeclampsia in a Racially Diverse Population [PDF]

, 2013
Haptoglobin's (Hp) antioxidant and pro-angiogenic properties differ between the 1-1, 2-1, and 2-2 phenotypes. Hp phenotype affects cardiovascular disease risk and treatment response to antioxidant vitamins in some non-pregnant populations.
Alan M. Peaceman, Anthony Sciscione, AP Levy, AP Levy, AP Levy, AR Rumbold, Brian M. Mercer, Catherine Y. Spong, Cees Oudejans, D Altman, D Beazley, DD Waters, DM Jensen, EM Wendland, George Saade, H Goldenstein, HK Ury, HT Depypere, J Villar, JA Simon, JC Hauth, JM Roberts, JM Roberts, JNK Rao, John M. Thorp, Jorge E. Tolosa, Kenneth J. Leveno, L Mosca, L Myatt, L Poston, LC Chappell, LC Chappell, LE Cahill, Leslie Myatt, M Knuist, Margaret Harper, Marshall W. Carpenter, MB Landon, MC Cid, MR Langlois, MT Raijmakers, Paula L. McGee, Philip Samuels, R Asleh, RE Gaensslen, RN Sammour, Robin E. Gandley, S Blum, S Blum, S Blum, S Gupta, S Yusuf, SE Maynard, Susan M. Ramin, Tracey L. Weissgerber, U Milman, Yoram Sorokin, YW Park   +57 more
core   +9 more sources

Evaluation of Novel Fetal Hemoglobin Inducer Drugs in Treatment of β-Hemoglobinopathy Disorders

International Journal of Hematology-Oncology and Stem Cell Research, 2013
Objective: The use of fetal hemoglobin (HbF) inducer drugs is considered as a novel approach in treatment of β-hemoglobinopathies, especially β- thalassemia and sickle cell disease. HbF inducers including hydroxyurea, histone deacetylase (HDAC) inhibitor
Fatemeh Salari, Mohammad Shahjahani, Seyed Ahmad Hosseini, Ali Dehghani Fard, Kaveh Jaseb   +4 more
doaj   +2 more sources

A Personalized Fluid-structure Interaction Modeling Paradigm for Aorta in Human Fetuses [PDF]

arXiv, 2023
Fluid-structure interaction (FSI) modeling, a technique widely used to enhance imaging modalities for adult and pediatric heart diseases, has been underutilized in the context of fetal circulation because of limited data on flow conditions and material properties.
arxiv  

Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia [PDF]

, 2012
This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfluidic approach.
Brognara, Eleonora, Capretto, Lorenzo, Carugo, Dario, Gambari, Roberto, Hill, Martyn, Lampronti, Ilaria, Mazzitelli, Stefania, Nastruzzi, Claudio, Zhang, Xunli   +8 more
core   +2 more sources

A common signaling pathway is activated in erythroid cells expressing high levels of fetal hemoglobin: a potential role for cAMP-elevating agents in β-globin disorders

Journal of Blood Medicine, 2013
Tohru Ikuta,1 Yuichi Kuroyanagi,1 Nadine Odo,1 Siyang Liu21Department of Anesthesiology and Perioperative Medicine, 2Department of Physiology, Medical College of Georgia, Georgia Regents University, Augusta, GA, USABackground: Although erythroid cells ...
Ikuta T, Kuroyanagi Y, Odo N, Liu S
doaj  

Diagnóstico não invasivo da anemia fetal pela medida do pico de velocidade sistólica na dopplervelocimetria da artéria cerebral média Noninvasive fetal anemia diagnosis by middle cerebral artery peak systolic velocity waveform measurement

Revista Brasileira de Ginecologia e Obstetrícia, 2004
OBJETIVO: avaliar se existe associação entre a medida do pico de velocidade sistólica (PVS) na dopplervelocimetria da artéria cerebral média (ACM) e a concentração de hemoglobina fetal e determinar a sua capacidade diagnóstica.
Marcos Roberto Taveira, Antônio Carlos Vieira Cabral, Henrique Vítor Leite, Isabela Gomes de Melo, Ana Paula Brum de Miranda Lopes   +4 more
doaj   +1 more source

Improved Fetal Hemoglobin With mTOR Inhibitor–Based Immunosuppression in a Kidney Transplant Recipient With Sickle Cell Disease

American Journal of Transplantation, 2017
Fetal hemoglobin induction is a key point in the management of sickle cell disease (SCD). We report the case of a kidney transplant recipient with SCD who was treated with everolimus, a mammalian target of rapamycin inhibitor.
N. Gaudré, P. Cougoul, P. Bartolucci, G. Dörr, A. Bura-Rivière, N. Kamar, A. Del Bello   +6 more
semanticscholar   +1 more source

PIPPI2021: An Approach to Automated Diagnosis and Texture Analysis of the Fetal Liver & Placenta in Fetal Growth Restriction [PDF]

arXiv, 2022
Fetal growth restriction (FGR) is a prevalent pregnancy condition characterised by failure of the fetus to reach its genetically predetermined growth potential. We explore the application of model fitting techniques, linear regression machine learning models, deep learning regression, and Haralick textured features from multi-contrast MRI for multi ...
arxiv  

Speciation in the baboon and its relation to gamma-chain heterogeneity and to the response to induction of HbF by 5-azacytidine [PDF]

, 1984
In the baboon (Papio species), the two nonallelic gamma-genes produce gamma-chains that differ at a minimum at residue 75, where isoleucine (I gamma-chain) or valine (V gamma) may be present.
DeSimone, Joseph, Espinueva, Zenaida, Hall, Lemuel, Huynh, Van, Schroeder, W. A., Shelton, J. Roger, Shelton, Joan B., Zwiers, David   +7 more
core  

Conference scene : Golden Helix Pharmacogenomics Days : educational activities on pharmacogenomics and personalized medicine [PDF]

, 2012
The Golden Helix Pharmacogenomics Days are high-profile international educational scientific meetings discussing pharmacogenomics and personalized medicine.
Borg, Joseph J., Fenech, Anthony G., Grech, Godfrey, Patrinos, George P., Severino, Giovanni, Squassina, Alessio   +5 more
core   +2 more sources