Results 101 to 110 of about 819,369 (331)

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

The Difference of Hematocrit in Term and Preterm Vaginal Births in Different Timing of Delayed Cord Clampin

Thai Journal of Obstetrics and Gynaecology, 2015
Objective:To compare fetal hematocrit in different timing of delayed cord clamping and fetomaternal outcome at 48 hours after vaginal births.Materials and Methods: 200 term and preterm vaginal births were recruited by inclusion criteria and ...
Somprattana Mungkornkaew, Theera Siwadune   +1 more
doaj   +1 more source

A new hereditary persistence of fetal hemoglobin deletion has the breakpoint within the 3' beta-globin gene enhancer [PDF]

, 1990
Clara Camaschella, Angelo Serra, E Gottardi, A Alfarano, D. Revello, U Mazza, Giuseppe Saglio   +6 more
openalex   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

Epigenetic modulations on the fetal hemoglobin induction [PDF]

International Journal of Hematology-Oncology and Stem Cell Research, 2012
In recent years of experience fetal hemoglobin (HbF) induction considers as novel therapeutic approach for β-thalassemia and sickle cell in therapeutic approaches.
Najmaldin Saki, Mehrdad Noruzinia, Saeid Kaviani, Ali Dehghani Fard, Esmaeil Mortaz   +4 more
doaj   +2 more sources

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Cálculo do volume de sangue necessário para a correção da anemia fetal em gestantes isoimunizadas Blood volume calculation required for the correction of fetal anemia in pregnant women with alloimmunization

Revista Brasileira de Ginecologia e Obstetrícia, 2008
OBJETIVO: obter uma equação capaz de estimar o volume de concentrado de hemácias a ser infundido para correção da anemia em fetos de gestantes portadoras de isoimunização pelo fator Rh, baseado em parâmetros alcançados durante a cordocentese prévia à ...
Mônica Deolindo Santiago, Cezar Alencar de Lima Rezende, Antônio Carlos Vieira Cabral, Henrique Vitor Leite, Zilma Nogueira dos Reis Vitral, Isabela Melo Apocalypse   +5 more
doaj   +1 more source

[Fetal hemoglobin].

Postepy higieny i medycyny doswiadczalnej, 1991
The paper presents a current state of knowledge on the regulation of Hb synthesis in physiology and pathology. Possible mechanisms of HbF synthesis switching and an influence of different drugs on HbF production have been described.
openaire   +1 more source

Serum erythropoietin and erythropoiesis in high- and low-fetal hemoglobin beta-thalassemia intermedia patients [PDF]

, 1994
R. Galanello, Susanna Barella, MP Turco, N. Giagu, A Cao, Sylvain Doré, NL Liberato, Roberta Guarnone, Giovanni Barosi   +8 more
openalex   +1 more source

Establishment of diagnostic cut off values of MCV, Fetal hemoglobin and Red Cell Width Distribution for HbE disease and HbE trait.

, 2023
Biswas Teresa, Thakuria Ghanashyam
openalex   +1 more source