Results 61 to 70 of about 72,054 (299)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Revista Brasileira de Ginecologia e Obstetrícia, 2005 OBJETIVO: estabelecer novo marcador não invasivo na detecção da anemia fetal, em gestantes isoimunizadas por antígenos eritrocitários. MÉTODOS: em estudo transversal o índice ecográfico obtido pela razão entre a medida ecográfica do diâmetro ...
Antônio Carlos Vieira Cabral +4 more
doaj +1 more source
Advanced Functional Materials, EarlyView.An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández +14 more
wiley +1 more source
Flipping the Hemoglobin Switch and Discovering Regulators Involved in Fetal Hemoglobin Reactivation [PDF]
, 2020 The fetal to adult hemoglobin switch is a developmental process by which fetal hemoglobin becomes silenced after birth and replaced by adult hemoglobin.
Boontanrart, Mandy
core
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
The effects of fetal hemoglobin levels on sickle cell anemia patients bone biochemistry [Fetal hemoglobin seviyesinin orak hücre anemisi hastalarının kemik biyokimyası üzerine etkisi] [PDF]
, 2016 Objective: The aim of this study was to evaluate the possible roles of fetal hemoglobin levels on bone parameters in sickle cell anemia (SCA) patients.
Kökbaş U. +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He +9 more
wiley +1 more source
Serum of sickle cell disease patients contains fetal hemoglobin silencing factors secreted from leukocytes [PDF]
, 2018 Tohru Ikuta,1 Hassan Sellak,1 Si-Yang Liu,2 Nadine Odo1 1Department of Anesthesiology and Perioperative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, USA; 2Department of Biochemistry and Molecular Biology, Medical College of ...
Ikuta T, Odo N, Liu SY, Sellak H
core
Fetal hemoglobin levels during study period. [PDF]
, 2016 Fetal hemoglobin levels were assessed with hemoglobin electrophoresis for the A) 50g, B) 100g, and C) 150g cohorts. Each individual patient is designated with letter, symbol, and color codes; several patients participated in multiple cohorts.
Marilyn J. Telen (48984) +5 more
core +1 more source