Results 41 to 50 of about 72,054 (299)
IJRETINA (International Journal of Retina), 2023 Introduction: The objective of this study was to find an association of fetal hemoglobin (HbF) with gestational age, birth weight and retinopathy of prematurity (ROP) in preterm infants. Methods: Observational prospective study. We included a total of
Nishi Prasad +3 more
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Hemoglobin: A Biochemical and Molecular Overview [PDF]
, 2020 This book brings together a selection of chapters dedicated to fetal hemoglobin - its physiological role, regulation, methodologies to manipulate and future strategies.No Full ...
Rahman, Motiur +4 more
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Cell free hemoglobin in the fetoplacental circulation: a novel cause of fetal growth restriction? [PDF]
, 2018 Cell free hemoglobin impairs vascular function and blood flow in adult cardiovascular disease. In this study, we investigated the hypothesis that free fetal hemoglobin (fHbF) compromises vascular integrity and function in the fetoplacental circulation ...
Greenwood, Susan L +14 more
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Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia
Hematology, Transfusion and Cell Therapy, 2021 Introduction: Sickle cell anemia (SCA) is a Mendelian disorder with a heterogeneous clinical course. The reasons for this phenotypic diversity are not entirely established, but it is known that high fetal hemoglobin levels lead to a milder course of the ...
Diego A. Pereira-Martins +9 more
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Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model
Haematologica, 2010 Hydroxyurea has proven clinical efficacy in patients with sickle cell disease. Potential mechanisms for the beneficial effects include fetal hemoglobin induction and the reduction of cell adhesive properties, inflammation and hypercoagulability.
Jeffrey D. Lebensburger +4 more
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Metabolic persistence of fetal hemoglobin [PDF]
Blood, 1995 Hereditary persistence of fetal hemoglobin (HPFH) has typically been ascribed to mutations in the beta-globin gene cluster. Pharmacologic agents, including the short-chain fatty acid butyrate, have been shown to upregulate fetal and embryonic globin gene expression. In this report we investigate the possibility that metabolic derangements characterized
J A, Little +3 more
openaire +2 more sources
Agreement between HbA1c measured by DCA 2000 and by HPLC: effects of fetal hemoglobin concentrations [PDF]
, 2004 In subjects with type 1 diabetes, persisting elevations of fetal hemoglobin (HbF) have been demonstrated. This study evaluated whether HbF levels typically seen in type 1 diabetes (up to 3%) interfere with glycohemoglobin determinations using a common ...
Wälchli, M +3 more
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What influences Hb fetal production in adulthood?
Revista Brasileira de Hematologia e Hemoterapia, 2011 Human hemoglobin genes are located in α and β globin gene clusters in chromosomes 16 and 11, respectively. Different types of hemoglobin are synthesized according to the stage of development with fetal hemoglobin (α2γ2) (Hb F) being ...
Gisele Cristine de Souza Carrocini +2 more
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Oxidative stress in preeclampsia and the role of free fetal hemoglobin
Frontiers in Physiology, 2015 Preeclampsia is a leading cause of pregnancy complications and affects 3–7 % of pregnant women. This review summarizes the current knowledge of a new potential etiology of the disease, with a special focus on hemoglobin-induced oxidative stress ...
Stefan Rocco Hansson +2 more
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Haematological Characterisation and Molecular Basis of Asian Indian Inversion Deletions Delta Beta Thalassemia: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2014 The hereditary persistence of fetal hemoglobin (HPFH) and delta beta thalassemia are heterogeneous disorders characterised by increased levels of fetal hemoglobin and high level of this Hb continues in adulthood.
Jitender Mohan Khunger +4 more
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