Results 21 to 30 of about 115,549 (302)
Revista Brasileira de Hematologia e Hemoterapia, 2012 BACKGROUND: Sickle cell disease is a hemoglobinopathy characterized by hemolytic anemia, increased susceptibility to infections and recurrent vaso-occlusive crises that reduces the quality of life of sufferers.
Darcielle Bruna Dias Elias +5 more
doaj +1 more source
Breaking Free from Your Fetal Chains: A Case-Based Review of the Literature on Gamma Chain Variant Hemoglobinopathies [PDF]
Neonatal Medicine, 2023 Methemoglobinemia is a dyshemoglobinemia characterized by cyanosis and reduced oxygen saturation with increased methemoglobin values. The etiology may be congenital or acquired, with the latter being more common.
Pearl Mary Varughese +3 more
doaj +1 more source
Keeping fetal hemoglobin in the loop [PDF]
Cell Cycle, 2014 Sickle cell disease (SCD) is caused by a point mutation in the adult type β-globin gene. The faulty β-globin chain triggers hemoglobin polymerization, promoting red blood cell sickling. Altered red blood cell shape causes occlusion of small blood vessels, leading to multi-organ damage and limiting life expectancy to 40–50 y of age.
Jeremy D, Grevet, Gerd A, Blobel
openaire +2 more sources
Effects of maternal subnutrition during early pregnancy on cow hematological profiles and offspring physiology and vitality in two beef breeds [PDF]
, 2019 This experiment evaluated the effects of subnutrition during early gestation on hematology in cows (Bos Taurus) and on hematological, metabolic, endocrine, and vitality parameters in their calves.
Almaguer C. +9 more
core +2 more sources
Sickle cell disease and fetal hemoglobin
Saudi Journal of Medicine and Medical Sciences, 2018 Alicia Rivera
doaj +3 more sources
Micronutrient Intake and Fundal Height Determine Birth Weight [PDF]
, 2019 The birth weight (BW) are utilized as indicators of the healthy and term newborns. Factor that affects the weight of a newborn are micronutrient intake and fundal height. Folic acid and iron (Fe) were associated with newborn birth weight.
Aghadiati, F. (Faradina) +2 more
core +3 more sources
Molecular Therapy: Methods & Clinical Development, 2019 Elements within the γ-hemoglobin promoters (HBG1 and HBG2) function to bind transcription complexes that mediate repression of fetal hemoglobin expression. Sickle cell disease (SCD) subjects with a 13-bp deletion in the HBG1 promoter exhibit a clinically
Christopher T. Lux +13 more
doaj +1 more source
Hepcidin and iron homeostasis during pregnancy. [PDF]
, 2014 Hepcidin is the master regulator of systemic iron bioavailability in humans. This review examines primary research articles that assessed hepcidin during pregnancy and postpartum and report its relationship to maternal and infant iron status and birth ...
Cadwell, Brooke +4 more
core +1 more source
IJRETINA (International Journal of Retina), 2023 Introduction: The objective of this study was to find an association of fetal hemoglobin (HbF) with gestational age, birth weight and retinopathy of prematurity (ROP) in preterm infants. Methods: Observational prospective study. We included a total of
Nishi Prasad +3 more
doaj +1 more source
Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia
Hematology, Transfusion and Cell Therapy, 2021 Introduction: Sickle cell anemia (SCA) is a Mendelian disorder with a heterogeneous clinical course. The reasons for this phenotypic diversity are not entirely established, but it is known that high fetal hemoglobin levels lead to a milder course of the ...
Diego A. Pereira-Martins +9 more
doaj +1 more source