Results 31 to 40 of about 795,751 (338)

Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner

Journal of Pineal Research, 2022
Insufficient oxygen supply (hypoxia) during fetal development leads to cardiac remodeling and a predisposition to cardiovascular disease in later life. Previous work has shown hypoxia causes oxidative stress in the fetal heart and alters the activity and
K. L. Smith, Agnieszka Swiderska, Mitchell C Lock, L. Graham, Wulan Iswari, Tashi Choudhary, Donna Thomas, Hager M. Kowash, M. Desforges, E. Cottrell, A. Trafford, D. Giussani, G. Galli   +12 more
semanticscholar   +1 more source

Impaired Cell Cycle Progression and Self-Renewal of Fetal Neural Stem and Progenitor Cells in a Murine Model of Intrauterine Growth Restriction

Frontiers in Cell and Developmental Biology, 2022
Individuals with intrauterine growth restriction (IUGR) are at an increased risk for neurodevelopmental impairment. Fetal cortical neurogenesis is a time-sensitive process in which fetal neural stem cells (NSCs) follow a distinct pattern of layer ...
Fu-Sheng Chou, Fu-Sheng Chou, Chu-Yen Chen, An-Chun Lee, Pei-Shan Wang   +4 more
doaj   +1 more source

Fetal hypoxia: Temperature value for oxygen exchange, resistance to hypoxic damage, and diagnostics using a thermal imager

Indian Journal of Obstetrics and Gynecology Research, 2020
Modernization of obstetric care for fetal hypoxia is proposed by hyperventilating the mother’s lungs with oxygen before the first symptoms of oxygen poisoning, General hypothermia of her body, and local hypothermia of the fetal head in the final period ...
A. Urakov, N. Urakova
semanticscholar   +1 more source

Effects of Prenatal Hypoxia on Nervous System Development and Related Diseases

Frontiers in Neuroscience, 2021
The fetal origins of adult disease (FOAD) hypothesis, which was proposed by David Barker in the United Kingdom in the late 1980s, posited that adult chronic diseases originated from various adverse stimuli in early fetal development.
Bin Wang, Hongtao Zeng, Jingliu Liu, Miao Sun   +3 more
doaj   +1 more source

The fetal brain sparing response to hypoxia: physiological mechanisms

Journal of Physiology, 2015
Dino A. Giussani
openalex   +3 more sources

A Simplified Paradigm of Late Gestation Transient Prenatal Hypoxia to Investigate Functional and Structural Outcomes from a Developmental Hypoxic Insult

Bio-Protocol, 2022
Late-gestation transient intrauterine hypoxia is a common cause of birth injury. It can lead to long-term neurodevelopmental disabilities even in the absence of gross anatomic injury. Currently, postnatal models of hypoxia–ischemia are most commonly used
Elyse Gadra, Ana Cristancho
doaj   +1 more source

Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys

Frontiers in Physiology, 2017
Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture.
Kiumars Shamloo, Juan Chen, Jasmine Sardar, Rinzhin T. Sherpa, Rajasekharreddy Pala, Kimberly F. Atkinson, William J. Pearce, Lubo Zhang, Surya M. Nauli, Surya M. Nauli   +9 more
doaj   +1 more source

Effect of Fish Oil on Hypoxia-Induced Apparent Congenital Abnormalities and Fetal Body Dimensions during Gestation in Rat

مجله دانشگاه علوم پزشکی گرگان, 2022
Background and Objective: Hypoxia is one of the most common clinical stresses that occur during pregnancy, which has adverse effects on fetal development. Fish oil, with its antioxidant properties, prevents fetal disorders during pregnancy.
Kaveh Khazaeel, Abbas Sadeghi, Zohreh Ghotbeddin, Hoshyar Yaghoubi   +3 more
doaj  

Antenatal Hypoxia Accelerates the Onset of Alzheimer’s Disease Pathology in 5xFAD Mouse Model

Frontiers in Aging Neuroscience, 2020
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder associated with cognitive impairment and later dementia among the elderly. Mounting evidence shows that adverse maternal environments during the fetal development increase the risk of ...
Guofang Shen, Shirley Hu, Zhen Zhao, Lubo Zhang, Qingyi Ma   +4 more
doaj   +1 more source

Gestational Hypoxia and Blood-Brain Barrier Permeability: Early Origins of Cerebrovascular Dysfunction Induced by Epigenetic Mechanisms

Frontiers in Physiology, 2021
Fetal chronic hypoxia leads to intrauterine growth restriction (IUGR), which is likely to reduce oxygen delivery to the brain and induce long-term neurological impairments.
Emilio A. Herrera, Alejandro González-Candia   +1 more
doaj   +1 more source