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The Fetal Inflammatory Response Syndrome
Clinical Obstetrics & Gynecology, 2007The fetal inflammatory response syndrome (FIRS) is a condition characterized by systemic inflammation and an elevation of fetal plasma interleukin-6. This syndrome has been observed in fetuses with preterm labor with intact membranes, preterm prelabor rupture of the membranes, and also fetal viral infections such as cytomegalovirus.
Gotsch, F. +7 more
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Morbidity in preterm infants with fetal inflammatory response syndrome
Pediatrics International, 2016AbstractBackgroundThe aim of this study was to evaluate the relationship between umbilical cord blood interleukin (IL)‐6 concentration and preterm morbidity and mortality in premature infants born with fetal inflammatory response syndrome (FIRS).MethodsThis prospective, observational study included 84 preterm infants with a gestational age of 24–36 ...
Elif, Ozalkaya +4 more
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Diagnostic accuracy of amniotic fluid interleukin‐6 for fetal inflammatory response syndrome
Journal of Obstetrics and Gynaecology Research, 2023AbstractAimThis study aimed to clarify the diagnostic accuracy of amniotic fluid interleukin‐6 for fetal inflammatory response syndrome (FIRS).MethodsThis retrospective cohort study was conducted in a single institution and targeted cases of preterm birth within 24 h after amniocentesis among singleton cases that underwent amniocentesis at our hospital
Kana Ohkuma +9 more
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Fetal inflammatory response syndrome (FIRS): che cosa è, quando bisogna pensarci
Medico e Bambino Pagine elettroniche, 2022The paper describes a case of severe hyperleukocytosis in a preterm with FIRS (Fetal Inflammatory Response Syndrome) associated with funisitis of umbilical cord and intrauterine inflammation. FIRS is a cause of leukocytosis in newborn, as well as leukemoid reaction in 21 trisomy, congenital leukemia, sepsis and steroid prophylaxis.
Tagliani, Sara +7 more
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Neurologic outcome after fetal inflammatory response syndrome: Trimester-specific considerations
Seminars in Fetal and Neonatal Medicine, 2020Clinical signs and neuroimaging patterns associated with the fetal inflammatory response syndrome (FIRS) worsen or mimic the clinical repertoire after intrapartum hypoxic-ischemic encephalopathy (HIE) during labor and/or parturition. Diagnostic considerations expressed as neonatal encephalopathy (NE) must consider chronic as well as acute factors ...
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Premature Birth and the Fetal Inflammatory Response Syndrome
NeoReviews, 2016This review focuses on the subset of infected premature infants who suffer from the fetal inflammatory response syndrome (FIRS), which is defined as an acute systemic inflammatory response to intra-amniotic fluid infection. The typical patient with FIRS is premature and has an elevated level of fetal plasma interleukin 6, neutrophilia, suspected or ...
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Fetal Inflammatory Response Syndrom: Leidet die zerebrale Sauerstoffversorgung?
Zeitschrift für Geburtshilfe und Neonatologie, 2020Ein sogenanntes FIRS (fetal inflammatory response syndrome) liegt per Definition vor, wenn in Folge einer systemischen Aktivierung des fetalen Immunsystems im Nabelschnurblut erhöhte Interleukin-6(IL-6)-Spiegel gemessen werden. Die betroffenen Kinder haben ein erhöhtes
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Preterm Labor, Intrauterine Infection, and the Fetal Inflammatory Response Syndrome
NeoReviews, 2002After completing this article, readers should be able to: 1. Describe the components of the common terminal pathway of human parturition. 2. Define the preterm parturition syndrome. 3. Describe the pathways of intrauterine infection. 4. Explain the relationship between intrauterine infection and preterm birth. 5.
Roberto Romero, Tinnakorn Chaiworapongsa
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Journal of Perinatal Medicine, 2005
To confirm previous known relationships between Fetal Inflammatory Response Syndrome (FIRS) and neonatal bronchopulmonary dysplasia (BPD) and to present information on previously unknown special relationships between inflammatory variables and BPD.At delivery, we obtained biological specimens including umbilical cord venous blood for plasma interleukin-
Robert, Mittendorf +6 more
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To confirm previous known relationships between Fetal Inflammatory Response Syndrome (FIRS) and neonatal bronchopulmonary dysplasia (BPD) and to present information on previously unknown special relationships between inflammatory variables and BPD.At delivery, we obtained biological specimens including umbilical cord venous blood for plasma interleukin-
Robert, Mittendorf +6 more
openaire +2 more sources
[New clinical entity in perinatology: fetal inflammatory response syndrome].
Orvosi hetilap, 2003In spite of the adequate therapy serious inflammatory complications affect the majority of preterm neonates. Recently, the role of fetal inflammatory response syndrome has been emerged as a possible mechanism. This new clinical entity is characterised by the generalised activation of fetal immune system which is often the result of chorioamnionitis ...
Gábor, Erdei +2 more
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