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The fetal inflammatory response syndrome
American Journal of Obstetrics and Gynecology, 1998 The objective of this study was to determine the frequency and clinical significance of a systemic inflammatory response as defined by an elevated plasma interleukin-6 concentration in fetuses with preterm labor or preterm premature rupture of membranes.Amniocenteses and cordocenteses were performed in 157 patients with preterm labor and preterm ...
Ricardo Gomez +2 more
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Fetal thymic involution: A sonographic marker of the fetal inflammatory response syndrome
American Journal of Obstetrics and Gynecology, 2006 The purpose of this study was to evaluate whether there is a relationship between the sonographic fetal thymus size and the presence of an intrauterine infection in patients with preterm labor.Thirty-one women who had been admitted with preterm labor and intact membranes between 24 and 32 weeks of gestation were included.
Edoardo Di Naro +2 more
exaly +8 more sources
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Cerebral palsy and fetal inflammatory response syndrome: a review
Journal of Perinatal Medicine, 2006Cerebral palsy (CP) is the most common cause of severe physical disability in childhood. The precise etiological factor for the development of the majority of cases of CP has not been identified, however, prematurity is considered to be the leading identifiable risk factor. During the last decade, intrauterine infection/inflammation has been identified
Asher Bashiri, Eliezer Burstein
exaly +3 more sources
Journal of Maternal-Fetal and Neonatal Medicine, 2002
To determine whether there is a relationship between the presence of histological signs of inflammation in the extraplacental membranes and umbilical cord and the concentrations of fetal plasma interleukin-6 (IL-6).The study examined a cohort of patients who were admitted with preterm labor or preterm premature rupture of the membranes (PROM) and who ...
T Chaiworapongsa +2 more
exaly +6 more sources
To determine whether there is a relationship between the presence of histological signs of inflammation in the extraplacental membranes and umbilical cord and the concentrations of fetal plasma interleukin-6 (IL-6).The study examined a cohort of patients who were admitted with preterm labor or preterm premature rupture of the membranes (PROM) and who ...
T Chaiworapongsa +2 more
exaly +6 more sources
The fetal inflammatory response syndrome is a risk factor for morbidity in preterm neonates
American Journal of Obstetrics and Gynecology, 2013The aim of this study was to show and discuss an association between fetal inflammatory response syndrome (FIRS) and an adverse neonatal outcome defined as combined severe neonatal morbidity and mortality in preterm neonates hospitalized in our neonatal intensive care unit.This was an observational study including all preterm neonates hospitalized in ...
Nora Hofer +2 more
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Seminars in Fetal and Neonatal Medicine, 2020
The fetal inflammatory response syndrome (FIRS) is characterized by umbilical cord inflammation and elevated fetal pro-inflammatory cytokines. Surviving neonates, especially very preterm infants, have increased rates of neonatal morbidity including neurodevelopmental impairment. The mechanism of brain injury in FIRS is complex and may involve "multiple
Vivien, Yap, Jeffrey M, Perlman
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The fetal inflammatory response syndrome (FIRS) is characterized by umbilical cord inflammation and elevated fetal pro-inflammatory cytokines. Surviving neonates, especially very preterm infants, have increased rates of neonatal morbidity including neurodevelopmental impairment. The mechanism of brain injury in FIRS is complex and may involve "multiple
Vivien, Yap, Jeffrey M, Perlman
exaly +3 more sources
American Journal of Obstetrics and Gynecology, 2016
In patients with preterm premature rupture of membranes, intrauterine inflammation and/or infection is frequently present, can lead to fetal inflammatory response syndrome, and is associated with adverse neonatal outcome. Clinical decision making requires balancing the potential benefits of pregnancy prolongation against the risk of intrauterine ...
Mirjam Kunze +2 more
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In patients with preterm premature rupture of membranes, intrauterine inflammation and/or infection is frequently present, can lead to fetal inflammatory response syndrome, and is associated with adverse neonatal outcome. Clinical decision making requires balancing the potential benefits of pregnancy prolongation against the risk of intrauterine ...
Mirjam Kunze +2 more
exaly +4 more sources
Pediatric and Developmental Pathology, 2009
Immature delivery is frequently associated with a maternal-fetal inflammatory response at the placental level. The aims of this study were to determine the prevalence, staging, and grading of histological findings (associated with acute maternal-fetal inflammatory response syndrome) in placentas of immature fetuses and to establish the relationship ...
Rosa B, Fuksman, Nancy G, Mazzitelli
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Immature delivery is frequently associated with a maternal-fetal inflammatory response at the placental level. The aims of this study were to determine the prevalence, staging, and grading of histological findings (associated with acute maternal-fetal inflammatory response syndrome) in placentas of immature fetuses and to establish the relationship ...
Rosa B, Fuksman, Nancy G, Mazzitelli
exaly +3 more sources
Neuroimaging findings associated with the fetal inflammatory response syndrome
Seminars in Fetal and Neonatal Medicine, 2020The fetal inflammatory response syndrome (FIRS) is a condition whereby the fetus mounts an inflammatory response to intrauterine infection/inflammation. Clinical consequences include preterm premature rupture of membranes (PPROM), spontaneous preterm delivery, neonatal sepsis, bronchopulmonary dysplasia, and brain and other organ injury.
Luis F, Goncalves +2 more
openaire +2 more sources