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Medico-legal implications of the fetal inflammatory response syndrome
Seminars in Fetal and Neonatal Medicine, 2020Babies who sustain long term neurologic injury and disability are frequent subjects in medical malpractice litigation. In the United States, the tort system enables adjudication of claims through a proscribed system. This paper will review salient elements of the tort system-duty, breach, causation, and damages- and how they apply to encephalopathic ...
Jonathan M, Fanaroff, Steven M, Donn
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Therapeutic interventions for fetal inflammatory response syndrome (FIRS)
Seminars in Fetal and Neonatal Medicine, 2020Fetal inflammatory response syndrome (FIRS) is a condition defined by systemic inflammation in the fetus, a rapid increase of pro-inflammatory cytokines into the fetal circulation (including interleukin-1 and interleukin-6), as well as a cellular response (such as increased neutrophils, monocyte/macrophages, and T cells) and the presence of funisitis ...
Ying, Xiong, Pia, Wintermark
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The Fetal Inflammatory Response Syndrome
Clinical Obstetrics & Gynecology, 2007The fetal inflammatory response syndrome (FIRS) is a condition characterized by systemic inflammation and an elevation of fetal plasma interleukin-6. This syndrome has been observed in fetuses with preterm labor with intact membranes, preterm prelabor rupture of the membranes, and also fetal viral infections such as cytomegalovirus.
Gotsch, F. +7 more
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Morbidity in preterm infants with fetal inflammatory response syndrome
Pediatrics International, 2016AbstractBackgroundThe aim of this study was to evaluate the relationship between umbilical cord blood interleukin (IL)‐6 concentration and preterm morbidity and mortality in premature infants born with fetal inflammatory response syndrome (FIRS).MethodsThis prospective, observational study included 84 preterm infants with a gestational age of 24–36 ...
Elif, Ozalkaya +4 more
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Diagnostic accuracy of amniotic fluid interleukin‐6 for fetal inflammatory response syndrome
Journal of Obstetrics and Gynaecology Research, 2023AbstractAimThis study aimed to clarify the diagnostic accuracy of amniotic fluid interleukin‐6 for fetal inflammatory response syndrome (FIRS).MethodsThis retrospective cohort study was conducted in a single institution and targeted cases of preterm birth within 24 h after amniocentesis among singleton cases that underwent amniocentesis at our hospital
Kana Ohkuma +9 more
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Premature Birth and the Fetal Inflammatory Response Syndrome
NeoReviews, 2016This review focuses on the subset of infected premature infants who suffer from the fetal inflammatory response syndrome (FIRS), which is defined as an acute systemic inflammatory response to intra-amniotic fluid infection. The typical patient with FIRS is premature and has an elevated level of fetal plasma interleukin 6, neutrophilia, suspected or ...
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Preterm Labor, Intrauterine Infection, and the Fetal Inflammatory Response Syndrome
NeoReviews, 2002After completing this article, readers should be able to: 1. Describe the components of the common terminal pathway of human parturition. 2. Define the preterm parturition syndrome. 3. Describe the pathways of intrauterine infection. 4. Explain the relationship between intrauterine infection and preterm birth. 5.
Roberto Romero, Tinnakorn Chaiworapongsa
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Journal of Perinatal Medicine, 2005
To confirm previous known relationships between Fetal Inflammatory Response Syndrome (FIRS) and neonatal bronchopulmonary dysplasia (BPD) and to present information on previously unknown special relationships between inflammatory variables and BPD.At delivery, we obtained biological specimens including umbilical cord venous blood for plasma interleukin-
Robert, Mittendorf +6 more
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To confirm previous known relationships between Fetal Inflammatory Response Syndrome (FIRS) and neonatal bronchopulmonary dysplasia (BPD) and to present information on previously unknown special relationships between inflammatory variables and BPD.At delivery, we obtained biological specimens including umbilical cord venous blood for plasma interleukin-
Robert, Mittendorf +6 more
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Neurologic outcome after fetal inflammatory response syndrome: Trimester-specific considerations
Seminars in Fetal and Neonatal Medicine, 2020Clinical signs and neuroimaging patterns associated with the fetal inflammatory response syndrome (FIRS) worsen or mimic the clinical repertoire after intrapartum hypoxic-ischemic encephalopathy (HIE) during labor and/or parturition. Diagnostic considerations expressed as neonatal encephalopathy (NE) must consider chronic as well as acute factors ...
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Archives of Gynecology and Obstetrics, 2014
Intrauterine infection may induce the fetal inflammatory response syndrome (FIRS) and may cause cerebral palsy and bronchopulmonary dysplasia in newborns. The aim of the study was to evaluate the importance of FIRS for the early and later adaptation of preterms.Hundred and fifty-eight preterm infants, born at 22-34 weeks of gestation, were investigated
I, Pilypienė +6 more
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Intrauterine infection may induce the fetal inflammatory response syndrome (FIRS) and may cause cerebral palsy and bronchopulmonary dysplasia in newborns. The aim of the study was to evaluate the importance of FIRS for the early and later adaptation of preterms.Hundred and fifty-eight preterm infants, born at 22-34 weeks of gestation, were investigated
I, Pilypienė +6 more
openaire +2 more sources