Group B Streptococcus (GBS) is one of the most common bacteria isolated in human chorioamnionitis. Placental infection due to GBS is a major risk factor for fetal organ injuries, preterm birth, perinatal morbidity and mortality, and life-long multiorgan ...
Taghreed A. Ayash +4 more
doaj +1 more source
Systemic inflammatory responses to repeated and increasing endotoxin challenges in fetal sheep
Repeated low‐dose administration of lipopolysaccharide (LPS) attenuates subsequent fetal responses, which makes it challenging to investigate interventions to prolonged exposure.
Sanya Kathuria +7 more
doaj +1 more source
Differences in Whole Blood Gene Expression Associated with Infection Time-Course and Extent of Fetal Mortality in a Reproductive Model of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection. [PDF]
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant females causes fetal death and increased piglet mortality, but there is substantial variation in the extent of reproductive pathology between individual dams.
Jamie M Wilkinson +7 more
doaj +1 more source
Tei index to assess fetal cardiac performance in fetuses at risk for fetal inflammatory response syndrome [PDF]
AbstractObjectivesTo examine, in patients with premature rupture of the amniotic membranes (PROM) at < 34 weeks of gestation, the relationship between fetal myocardial performance measured by the Tei index and fetal inflammatory response syndrome (FIRS).MethodsA case–control study was conducted including 15 preterm PROM patients with gestational age
A L, Letti Müller +5 more
openaire +2 more sources
Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia +4 more
core +2 more sources
Introduction: Coronavirus disease 2019 (COVID-19), an extremely contagious pandemic, caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), originated from Wuhan, Hubei province, in China in December 2019.
Maitri Chaudhuri +4 more
doaj +1 more source
A lesson for cancer research : placental microarray gene analysis in preeclampsia [PDF]
Tumor progression and pregnancy share many common features, such as immune tolerance and invasion. The invasion of trophoblasts in the placenta into the uterine wall is essential for fetal development, and is thus precisely regulated.
Louwen, Frank +4 more
core +2 more sources
Significance of C-reactive protein in predicting fetal inflammatory response syndrome
The aim of the study was to identify and evaluate a possible correlation between C-reactive protein (CRP) concentration in maternal blood and the risk of developing fetal inflammatory syndrome (FIRS).The study included 158 infants born at 22-34 weeks of gestation and their mothers.
Daiva, Bartkeviciene +9 more
openaire +2 more sources
Inflammatory Response as a Mechanism of Perinatal Programming: Long-term Impact on Pulmonary and Renal Function? [PDF]
RATIONALE: Temporal changes in the fetal environment, such as malnutrition and placental insufficiency induce intrauterine growth restriction (IUGR) and lead to a permanent changes of physiological processes later in life.
Alejandre Alcázar, Miguel Angel
core
Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark +2 more
core

