Maternal‐driven immune education in offspring
Summary Maternal environmental exposures, particularly during gestation and lactation, significantly influence the immunological development and long‐term immunity of offspring. Mammalian immune systems develop through crucial inputs from the environment, beginning in utero and continuing after birth.
Krist Antunes Fernandes, Ai Ing Lim
wiley +1 more source
IN UTERO HAEMATOPOIETIC STEM CELL TRANSPLANTATION (IUHSCT)
In utero haematopoietic stem cell transplantation (IUHSCT) is a non-myeloablative approach for the prenatal treatment of genetic disorders. However, in target disorders, where there is not a selective advantage for donor cells, a useful donor-cell ...
Maria Concetta Renda, Aurelio Maggio
doaj +3 more sources
New insight into "allograft acceptance" and tolerance [PDF]
Discovery of microchimerism in kidney and liver transplantation provided an important framework for a better understanding of allograft acceptance, for analysis of managment problems and for therapeutically oriented transplanted research.
Starzl, TE
core
Donor hematopoietic progenitor cells in nonmyeloablated rat recipients of allogeneic bone marrow and liver grafts [PDF]
Background. Although the persistence of multilineage microchimerism in recipients of long-surviving organ transplants implies engraftment of migratory pluripotent donor stem cells, the ultimate localization in the recipient of these cells has not been ...
Demetris, AJ +5 more
core +1 more source
Pregnancy after liver transplantation under tacrolimus [PDF]
Background. The maternal and fetal risk of pregnancy after organ transplantation under tacrolimus has not been reported. This was prospectively studied in 27 pregnancies by 21 female liver recipients who were treated with tacrolimus before and throughout
Armenti +36 more
core +1 more source
Emerging Questions in Materno-Fetal Microchimerism [PDF]
Materno-fetal microchimerism is a common, life-long chimeric state first established by the exchange of small numbers of cells between the mother and the fetus during pregnancy. This apparently trivial phenomenon is now attracting attention due to its unexpected and profound implications in the immune system.
openaire +1 more source
On the potential origin of the zygote-like cancer stem cell with a focus on fusion for cell rescue
Cancer is conventionally viewed as a disease of accumulated somatic mutation and epigenetic dysregulation leading to cell de-differentiation and uncontrolled proliferation. With few exceptions, malignant tumors develop from a single damaged cell. However,
Cosmin Andrei Cismaru +5 more
doaj +1 more source
Cell migration and chimerism after whole‐organ transplantation: The basis of graft acceptance [PDF]
Improvements in the prevention or control of rejection of the kidney and liver have been largely interchangeable ( 1 , 2 ) and then applicable, with very little modification, to thoracic and other organs.
Demetris, AJ +13 more
core +1 more source
Fetal microchimeric cells influence maternal lung health following term and preterm births
Fetal microchimerism, the presence of fetal cells in maternal tissues, has garnered interest for its potential role in maternal physiology. In this study, we aimed to explore the impact of fetal microchimeric cells on maternal lung health following term ...
Ananth Kumar Kammala +7 more
doaj +1 more source
Fetal microchimerism, pregnancy epiphenomenon or kinship indicator? [PDF]
Burton GJ.
europepmc +1 more source

