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Identifying Key Questions and Challenges in Microchimerism Biology [PDF]

open access: yesAdvanced Science
Microchimerism research has recently gained renewed attention despite known existence of these rare cells for decades. Fetal and maternal microchimeric‐derived cells may have functional capabilities, and are increasingly associated with both beneficial ...
Kristine J. Chua   +31 more
doaj   +3 more sources

The Microchimerism Literature Atlas [PDF]

open access: yesBioinformatics and Biology Insights
The Microchimerism Literature Atlas (MCLA) is a comprehensive online dataset to facilitate the investigation of microchimerism (MC), condition where individuals harbor cells from another individual of the same species.
Michael Christian Gruber   +5 more
doaj   +5 more sources

Microchimerism, PERV and Xenotransplantation

open access: yesViruses, 2023
Microchimerism is the presence of cells in an individual that have originated from a genetically distinct individual. The most common form of microchimerism is fetomaternal microchimerism, i.e., cells from a fetus pass through the placenta and establish ...
Joachim Denner
doaj   +3 more sources

Clinical impact of early microchimerism dynamics after transplantation with enhanced dual-conditioning regimen in hematological diseases [PDF]

open access: yesFrontiers in Medicine
BackgroundMicrochimerism dynamics following allogeneic hematopoietic stem cell transplantation (allo-HSCT) may predict engraftment and clinical outcomes. This study aimed to quantify microchimerism changes and assess their clinical significance.MethodsIn
Yan Gu   +4 more
doaj   +2 more sources

“Lazarus Response” When Feto-Maternal Microchimerism Kicks in: Spontaneous Remission in Refractory Primary Mediastinal B Cell Lymphoma Following Twin Pregnancy [PDF]

open access: yesDiagnostics
Background: Spontaneous remission of cancer is a rare and poorly understood phenomenon characterized by complete or partial remission of a malignancy in the absence of or with inadequate treatment.
Radu Andrei Tomai   +14 more
doaj   +2 more sources

Pregnancy induced displacement of preexisting microchimeric cells in the absence of maternal B and T cells [PDF]

open access: yesFrontiers in Immunology
Bidirectional exchange of cells between mother and fetus occurs during pregnancy, and persistence of these genetically foreign cells establishes long-term microchimerism in both individuals after parturition.
Giang Pham   +5 more
doaj   +2 more sources

HLA-mismatched stem cell microtransplant prolonged overall survival and promoted immunological reconstitution for multiple myeloma [PDF]

open access: yesFrontiers in Immunology
BackgroundDespite advances in the treatment of multiple myeloma, a proportion of patients still hardly achieve desired prognosis. Although microtransplant (MST) has proved promising results in treating several hematological malignancies, it has not been ...
Yangyang Lei   +20 more
doaj   +2 more sources

Self or nonself: end of a dogma? [PDF]

open access: yesFrontiers in Immunology
Immunologists generally view the notion of self and non-self as part of a broader, more contextual understanding of immune function, rather than a rigid dogma.
Marie Duhamel   +2 more
doaj   +2 more sources

Microchimerism; Bilateral migration of cells between mother and fetus [PDF]

open access: yesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2022
Introduction: The bilateral cell traffic between fetus and mother probably occurs in all pregnancies and is participated in the development of fetal immune system, tissue repair in autoimmune diseases, cancer and maternal immune surveillance. Progressive
Solmaz Moniri Javadhesari   +1 more
doaj   +1 more source

Male microchimerism in the human female brain. [PDF]

open access: yesPLoS ONE, 2012
In humans, naturally acquired microchimerism has been observed in many tissues and organs. Fetal microchimerism, however, has not been investigated in the human brain.
William F N Chan   +5 more
doaj   +1 more source

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