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The outcomes of fetal cell microchimerism in the mother
The presence of small quantities of genetically heterogeneous cells in an organism is known as microchimerism. Fetal microchimerism is the presence of small quantities of fetal cells in the maternal system during and after pregnancy.
Anushka Nikhil Alekar
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HY immune tolerance is common in women without male offspring. [PDF]
Sex difference is an established risk factor for hematopoietic stem cell transplantation (HSCT)-related complications like graft versus host disease (GVHD). CD8pos cytotoxic T cells specific for Y chromosome-encoded minor Histocompatibility antigens (HY)
Miranda P Dierselhuis +6 more
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IntroductionThe study of immune response to SARSCoV-2 infection in different solid organ transplant settings represents an opportunity for clarifying the interplay between SARS-CoV-2 and the immune system.
Maria Rendina +62 more
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Microchimerism in Sjögren's syndrome [PDF]
The evidence of microchimerism both lends support to and raises doubts about its specific role in SS The advent of molecular biology techniques has led to the recognition that cells travel in both directions between mother and fetus. Fetal stem cells traverse the placenta and may persist in the maternal circulation for decades.
GIACOMELLI, Roberto +2 more
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Quantification of Female Chimeric Cells in the Tonsils of Male Children and Their Determinants
The factors influencing mother-to-child cell trafficking and persistence over children’s lives have yet to be established. The quantification of maternal microchimerism was previously reported through HLA-based approaches, which introduced bias regarding
Boris Dmitrenko +11 more
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AimsDuring pregnancy, fetal cells can migrate to the mother via blood circulation. A percentage of these cells survive in maternal tissues for decades generating a population of fetal microchimeric cells (fMCs), whose biological role is unclear.
Alessia Bianchi +14 more
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Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice
Interferon regulatory factor 2 binding protein 2 (Irf2bp2), a co-repressor of Irf2, is required for fetal hepatic erythropoiesis through the expansion of erythromyeloid progenitors. Mice with germline ablation of the entire Irf2bp2 transcript produced no
Ragnar O. Vilmundarson +26 more
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Chimerism after organ transplantation [PDF]
Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft.
Demetris, AJ +6 more
core +1 more source
Microchimerism and Endocrine Disorders [PDF]
The term "microchimerism" indicates the coexistence, in the same organism, of genetically distinct populations of cells derived from two different individuals. The passage of cells from the fetus to the mother is called fetal cell microchimerism, whereas that occurring from the mother to the fetus is named maternal cell microchimerism.
L. Fugazzola, V. Cirello, P. Beck-Peccoz
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Microchimerism, dendritic cell progenitors and transplantation tolerance [PDF]
The recent discovery of multilineage donor leukocyte microchimerism in allograft recipients up to three decades after organ transplantation implies the migration and survival of donor stem cells within the host.
Demetris, AJ +5 more
core +1 more source

