Results 171 to 180 of about 2,703 (208)
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Fetal cell microchimerism in human cancers
Cancer Letters, 2010The transfer of fetal cells into the maternal circulation occurs normally during pregnancy and the post-partum persistence of these cells in the maternal blood and tissues, known as fetal cell microchimerism, has been clearly demonstrated. However, the long-term consequences of this phenomenon are only beginning to be appreciated.
L. Fugazzola, V. Cirello, P. Beck Peccoz
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Fetal microchimerism as an explanation of disease
Nature Reviews Endocrinology, 2010Fetal cell microchimerism is defined as the persistence of fetal cells in the mother after birth without any apparent rejection. Fetal microchimeric cells (FMCs) engraft into the maternal bone marrow for decades after delivery and are able to migrate to blood and tissues.
L. Fugazzola, V. Cirello, P. Beck Peccoz
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Fetal microchimerism and inflammatory myopathies
The Lancet, 2001Albert Selva-O'Callaghan +4 more
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Maternal microchimerism in human fetal tissues
American Journal of Obstetrics and Gynecology, 2008The aim of the present study was to analyze the presence of maternal cells in human fetal tissues in the second trimester.Tissues from 11 second-trimester fetuses terminated because of social reasons or because of malformations and/or trisomy were investigated.
Anna Maria, Jonsson +4 more
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Fetal-cell microchimerism, lymphopoiesis, and autoimmunity
Archivum Immunologiae et Therapiae Experimentalis, 2009During all human and murine pregnancies, fetal cells enter the maternal circulation and tissues and may persist there for decades. The immune consequences of this phenomenon have been explored for many years as a potential origin of autoimmunity or protection from cancer in women after pregnancy.
Leduc, Michele +2 more
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Fetal Microchimerism and Women’s Health
Biological Research For Nursing, 2010Pregnancy is associated with transfer of maternal cells to the fetus and fetal cells to the mother. In both cases, the transferred cells are described as microchimeric. Fetal microchimeric cells include semi-allogeneic stem cells, which are few in number and are capable of long-term survival in the “foreign” host.
Maureen W, Groër +3 more
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Pathophysiology of fetal microchimeric cells
Clinica Chimica Acta, 2005Microchimerism has been defined by the presence of a low number of circulating cells transferred from one individual to another. The transfer of microchimeric cells naturally takes place during pregnancy and occurs bi-directionally between the mother and fetus.
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Fetal Microchimerism in Rheumatic Autoimmune Disease.
Nishi Nihon Hifuka, 2000当施設で経過観察中の男児出産歴のある全身性強皮症(SSc),全身性エリテマトーデス(SLE),シェーグレン症候群患者(SjS)を対象にfetal microchimerismを検討した。末梢血中に残存する胎児由来細胞を,Y染色体マーカー(DYZ 1)を用いて二段階PCR法にて検出した。さらにY染色体検出群,非検出群間の病型,臨床症状,自己抗体の差異について比較,検討した。結果,対照の健常者女性では20例中2例(10%)の末梢血抽出ゲノムDNA中にDYZ 1が検出されたのに対し,SSc患者17例中8例(47.7%)にDYZ 1配列が検出され,有意(p=0.031)に高頻度であった。またSLE 9例, SjS 4例の末梢血抽出ゲノムDNA中にDYZ 1配列は検出されなかった ...
Yuko MIYASHITA +3 more
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Maternal-Fetal Microchimerism and Fetal-Juvenile Malignancies
2012Maternal-fetal microchimerism has been discovered, when male (XY) cells were identified in the circulation and organs of mothers, who had sons and in the cord blood, circulation and organs of the newborns and sons.
György Berencsi, Erzsébet Barcsay
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Self-recognition and the role of fetal microchimerism
Best Practice & Research Clinical Endocrinology & Metabolism, 2004The course and severity of the autoimmune thyroid diseases (AITD) is known to be influenced by pregnancy as evidenced by disease suppression during pregnancy and initiation, or exacerbation, of disease postpartum. AITD is also known to affect both fertility and pregnancy outcome as evidenced by increased fetal loss.
Takao, Ando, Terry F, Davies
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