Results 91 to 100 of about 5,039 (204)

Effect of low and high-dose dexamethasone on cyp3a and p-glycoprotein expression and function in mice [PDF]

Eurasian Journal of Veterinary Sciences
Dexamethasone, which acts on nuclear receptors, is used together with P-gp and Cyp3a4 substrates at different doses in the treatment of diverse diseases.
Hatice Eser-Faki, Gonca Sonmez, Bunyamin Tras, Kamil Uney, Tugba Melike Parlak, Zeynep Ozdemir-Kutahya, Hakan Akbayrak   +6 more
doaj  

Formulation and Characterization of Fexofenadine hydrochloride Fast Dissolving Tablet by using various Superdisintegrants [PDF]

, 2012
In the present work, fast dissolving tablets of fexofenadine HCl were designed with a view to enhance patient compliance by direct compression method. The present work studied the effect of superdisintegrants on release rate of fexofenadine HCl in the ...
Pawar, S P; P.S.G.V.P.M,s College of Pharmacy, Shahada. Affiliated to North Maharashtra University, Jalgaon, Gaikwad, P D; P.S.G.V.P.M,s College of Pharmacy, Shahada. Affiliated to North Maharashtra University, Jalgaon, desale, kuldeep yogendra; P.S.G.V.P.M,s College of Pharmacy, Shahada. Affiliated to North Maharashtra University, Jalgaon, Bankar, V H; P.S.G.V.P.M,s College of Pharmacy, Shahada. Affiliated to North Maharashtra University, Jalgaon   +3 more
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Binding of fexofenadine hydrochloride to bovine serum albumin: structural considerations by spectroscopic techniques and molecular docking

, 2017
The binding interaction of peripheral H1 receptor antagonist drug, fexofenadine hydrochloride to bovine serum albumin (BSA) is investigated by fluorescence spectroscopy in combination with UV-absorption spectroscopy under physiological conditions.
Sharanappa T. Nandibewoor (660821), Laxmi N. Jattinagoudar (660819), Shivamurti A. Chimatadar (660822)   +2 more
core   +1 more source

A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice–Fexofenadine Interaction: An In Vitro–In Vivo “Connect” [PDF]

, 2013
The grapefruit juice (GFJ)–fexofenadine interaction involves inhibition of intestinal organic anion transporting polypeptide (OATP)-mediated uptake. Only naringin has been shown clinically to inhibit intestinal OATP; other constituents have not been ...
NC DOCKS at The University of North Carolina at Greensboro, Oberlies, Nicholas   +1 more
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CNS Side-effect of Fexofenadine, 180 mg Tablet

Siriraj Medical Journal, 1999
Fexofenadine, the derivative of terfenadine, has been shown to produce no side-effect on the heart, not distributed to the central nervous system (CNS), and having high selectivity for peripheral histamine H1-receptors.
B Dhorranintra, S Klyprayong
doaj  

Pharmacokinetics of fexofenadine following LPS administration to rats

The function and expression of drug transporters, including P-glycoprotein (P-gp) and organic-anion transporting polypeptides (Oatps), have been investigated but it is not well established how variables such as disease processes affect them. Fexofenadine
Gerber, Jacobus P, Davey, Andrew Keith, Jaisue, S   +2 more
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Quantitative determination of fexofenadine in human plasma by HPLC-MS

, 2007
A simple, rapid, sensitive and selective LC-MS method was developed and validated for quantification of fexofenadine in human plasma. The LC-MS system was operated under the positive electrospray ionisation mode (ESI).
Oezilhan, S., Oezden, T., Isleyen, E. A. Oe., Toptan, S.   +3 more
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Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate

, 2009
BACKGROUND: Although antihistamines are known for their sedative adverse effects, fexofenadine was previously shown to have stimulating effects. These stimulant effects were rather mild in magnitude and were only demonstrated in tasks with a high ...
van den Bergh, D., Ramaekers, J.G., de la Asuncion Elvira, J., Theunissen, E.L.; id_orcid, Dries van den Bergh, Eef L. Theunissen, Javier de la Asuncion Elvira, Johannes G. Ramaekers   +7 more
core   +1 more source

Combination of leukotriene receptor antagonists and antihistamines in management of allergic rhinitis - knowledge, attitude, and practice survey amongst healthcare professionals from India (COMB-AR)

The Journal of Association of Chest Physicians
Aim: To evaluate the perceived prevalence and common symptoms of allergic rhinitis (AR) in Indian adults, along with the role of the combination of leukotriene receptor antagonists and antihistamines in the management of AR symptoms.
Jafferhusein Sura, Yogesh Dabholkar, Nagendra Prasad K V, Deepesh Agrawal, Ved Prakash, Ashish Upadhyaya, Gurmeet Kaur Thakur, Vaishali Gupte   +7 more
doaj   +1 more source

Establishment of a human nasal epithelium model of histamine-induced inflammation to assess the activity of fexofenadine as an inverse agonist and its link to clinical benefit

Frontiers in Pharmacology
BackgroundFexofenadine (FEX) is an antihistamine that acts as an inverse agonist against histamine (HIS) receptor 1 (H1R), which mediates the allergic reaction.
Anne Barbot, Michele Lheritier-Barrand, Margarita Murrieta-Aguttes, Maud Leonetti, Jimmy Vernaz, Song Huang, Samuel Constant, Bernadett Boda   +7 more
doaj   +1 more source