Results 121 to 130 of about 59,586 (323)
Preferential arrangement of lipids in the long-periodicity phase of a stratum corneum matrix model
Journal of Lipid Research, 2018 The lipid matrix of the stratum corneum, the outermost skin layer, consists primarily of ceramides, cholesterol, and FFAs. These lipids form a trilayer long-periodicity phase (LPP) that is unique to this barrier.
Charlotte M. Beddoes +2 more
doaj +1 more source
Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes
Experimental &Molecular Medicine, 2017 Free fatty acids (FFAs) are important substrates for mitochondrial oxidative metabolism and ATP synthesis but also cause serious stress to various tissues, contributing to the development of metabolic diseases.
L. D. Ly +9 more
semanticscholar +1 more source
, 2013 AML12 cells were transfected with either miR-126 mimic, miR-24 inhibitor or their corresponding negative controls. 48 hs after transfection, FFAs (0.4 mM) was added and cells were incubated for another 18 hs.
Tingming Liang (219703) +2 more
core +1 more source
Epileptic Disorders, EarlyView.Abstract Pathogenic SV2A gene variants have been reported as causes of epilepsy and are often associated with drug resistance and susceptibility to fever‐related seizures. No highly effective treatments have been established for this condition. We report a female patient with a family history of epilepsy who developed generalized seizures associated ...
Takayuki Mori +4 more
wiley +1 more source
Changes in Plasma Free Fatty Acids Associated with Type-2 Diabetes
Nutrients, 2019 Type 2 diabetes mellitus (T2DM) is associated with increased total plasma free fatty acid (FFA) concentrations and an elevated risk of cardiovascular disease.
A. Sobczak +2 more
semanticscholar +1 more source
Production of biodiesel from vegetable oil and microalgae by fatty acid extraction and enzymatic esterification [PDF]
, 2015 The aim of this work was to obtain biodiesel (methyl esters) from the saponifiable lipids (SLs) fraction of the microalga Nannochloropsis gaditana, whose biomass dry weight contains 12.1 wt% of these lipids.
Esteban Cerdán, Luis +7 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku +4 more
wiley +1 more source
New Frontiers in Gut Nutrient Sensor Research: Free Fatty Acid Sensing in the Gastrointestinal Tract
Journal of Pharmacological Sciences, 2010 Utilizing the human genome database, the recently developed G-protein–coupled receptors (GPCRs) deorphanizing strategy successfully identified multiple receptors of free fatty acids (FFAs).
Satoshi Miyauchi +4 more
doaj +1 more source
Preparation of fatty acid methyl esters for gas-liquid chromatography[S]
Journal of Lipid Research, 2010 A convenient method using commercial aqueous concentrated HCl (conc. HCl; 35%, w/w) as an acid catalyst was developed for preparation of fatty acid methyl esters (FAMEs) from sterol esters, triacylglycerols, phospholipids, and FFAs for gas-liquid ...
K. Ichihara, Yumeto Fukubayashi
semanticscholar +1 more source
Epilepsia Open, EarlyView.Abstract Objective Stiripentol and fenfluramine are approved treatments for Dravet syndrome (DS), but real‐world data comparing their effectiveness and combined use remain limited. Our study aims to explore associations between treatment with stiripentol, fenfluramine, and their combination and clinical outcomes in patients with DS.
Paolo Surdi +7 more
wiley +1 more source