Results 241 to 250 of about 59,586 (323)
Liquiritigenin attenuates MASLD by activating AMPK and simultaneously inducing PPARα/PPARγ, thereby enhancing fatty acid oxidation, reducing hepatic steatosis and inflammation, and improving insulin sensitivity in HFD‐fed mice and FFA‐treated HepG2 cells.
Yu Jung Heo +8 more
wiley +1 more source
Association of three different dietary patterns with the metabolomic profiles of children: the BiomarKid project. [PDF]
Gheorghita I +13 more
europepmc +1 more source
James McGill Souness FFA [PDF]
openaire +1 more source
Individual differences in susceptibility to somatosensory false feedback (sFFB) predict altered network topography between regions previously implicated in sFFB. This work supports an interoceptive integration model of sFFB and highlights the importance of network topology in determining how individuals weigh and integrate internal and external ...
J. Patchitt +6 more
wiley +1 more source
Nanocurcumin (N‐Cur) mitigates Doxorubicin (DOX)‐induced cardiotoxicity by suppressing oxidative stress, inflammation, and histopathological damage in Wistar rats. Mechanistically, N‐Cur restores cardiomyocyte survival by activating the Wnt/β‐catenin signaling pathway and downregulating GSK‐3β expression.
Noha A. Alshuwayer +5 more
wiley +1 more source
Integrated Transcriptomics and Lipidomics Identify CES1-Mediated Maladaptive Lipolysis as a Key Target of Hyperlipidemic Acute Pancreatitis. [PDF]
Liu J, Zhang Y, Jiang X, Xue H, Yin P.
europepmc +1 more source
Hypertriglyceridaemia-Associated Acute Pancreatitis: Pathophysiological Insights and Advances in Clinical Management. [PDF]
Li Y +9 more
europepmc +1 more source
Spatial lipid-barrier coupling in knee osteoarthritis: a mechanism-based perspective centered on the infrapatellar fat pad. [PDF]
Liu Y, Chen M, Yong R.
europepmc +1 more source
Protein Lactylation in Cancer: From Mechanisms to Therapy
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang +8 more
wiley +1 more source

