Results 211 to 220 of about 35,769 (259)

A chondroprotective role for matrix-bound FGF2

open access: yes, 2016
Chia, S   +5 more
openaire   +1 more source

Signaling pathways implicated in PGF2α effects on Fgf2+/+ and Fgf2−/− osteoblasts

open access: yesJournal of Cellular Physiology, 2010
AbstractProstaglandin F2α (PGF2α) regulates fibroblast growth factor‐2 (FGF‐2) and fibroblast growth factor receptor (FGFR) expression in osteoblasts. Here, the role of FGF‐2 in PGF2α‐induced proliferation and the signaling pathway involved, were determined in calvarial osteoblasts (COBs) from Fgf2+/+ and Fgf2−/− mice.
SABBIETI, Maria Giovanna   +7 more
core   +6 more sources

Androgen receptor expression induces FGF2, FGF‐binding protein production, and FGF2 release in prostate carcinoma cells: Role of FGF2 in growth, survival, and androgen receptor down‐modulation

open access: yesThe Prostate, 2002
AbstractBACKGROUNDAlterations in fibroblast growth factors (FGFs) production and/or FGF receptors expression have been described to play key roles in prostate tumor progression, particularly in androgen‐independent tumors. However, the role of androgen receptor (AR) in altering FGF‐mediated growth and survival of prostatic neoplastic cells has not been
ROSINI P   +11 more
openaire   +8 more sources

Impaired bone anabolic response to parathyroid hormone in Fgf2−/− and Fgf2+/− mice

open access: yesBiochemical and Biophysical Research Communications, 2006
Since parathyroid hormone (PTH) increased FGF2 mRNA and protein expression in osteoblasts, and serum FGF-2 was increased in osteoporotic patients treated with PTH, we assessed whether the anabolic effect of PTH was impaired in Fgf2-/- mice. Eight-week-
C J Rosen   +2 more
exaly   +1 more source
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Maternal FGF2 levels associated with child anxiety and depression symptoms through child FGF2 levels

Journal of Affective Disorders, 2023
Recent research implicates fibroblast growth factor 2 (FGF2) in anxiety and depressive symptoms of childhood. This study is the first to examine an intergenerational pathway linking FGF2 levels in mothers to FGF2 levels in children, and to the children's anxiety and depressive symptoms.We assayed serum FGF2 in 259 mothers and their children, with a ...
Eli R, Lebowitz   +5 more
openaire   +2 more sources

Exostosin-like 2 regulates FGF2 signaling by controlling the endocytosis of FGF2

Biochimica et Biophysica Acta (BBA) - General Subjects, 2018
Heparan sulfate proteoglycans are ubiquitously expressed on cell surfaces and in extracellular matrices, and are engaged in heparin-binding growth factor-related signal transduction. Thus, changes in the amounts, structures, and chain lengths of heparan sulfate have profound effects on aspects of cell growth controlled by heparin-binding growth factors
Satomi, Nadanaka, Hiroshi, Kitagawa
openaire   +2 more sources

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