Results 81 to 90 of about 11,489 (185)

Fibroblast growth factor 23 weakens chemotaxis of human blood neutrophils in microfluidic devices

Scientific Reports, 2017
Neutrophil trafficking in tissues critically regulates the body’s immune response. Neutrophil migration can either play a protective role in host defense or cause health problems.
Ke Yang, Hagit Peretz-Soroka, Jiandong Wu, Ling Zhu, Xueling Cui, Michael Zhang, Claudio Rigatto, Yong Liu, Francis Lin   +8 more
doaj   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, Volume 59, Issue 10, October 2026.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Inflammation, iron and vitamin D metabolism in different cardiomyopathy aetiologies

Pteridines, 2020
Immune activation coincides with disturbances in iron and vitamin D metabolism in patients with cardiomyopathy. In this study, we investigated whether there are differences regarding immune activation, iron and vitamin D metabolism between the different ...
Lanser Lukas, Nemati Nada, Seifert Markus, Fuchs Dietmar, Weiss Günter, Pölzl Gerhard, Kurz Katharina   +6 more
doaj   +1 more source

Real‐World Effectiveness and Safety of Finerenone in People With Type 2 Diabetes and Chronic Kidney Disease: A Spanish Multicentre Retrospective Observational Study (MEDFINE‐RWD)

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9461-9472, October 2026.
ABSTRACT Aim Although finerenone has shown efficacy in randomized trials, evidence from routine clinical practice remains limited. We aimed to assess the real‐world effectiveness and safety of finerenone in people with type 2 diabetes (PWT2D) and chronic kidney disease (CKD), with a particular focus on residual cardiorenal risk as reflected by changes ...
Oscar Moreno‐Pérez, Antonio Tejera‐Muñoz, Patricia Tomás‐Gómez, Federico Vázquez‐San Miguel, Virginia Soria‐Utrilla, Ada María Roldán‐Sánchez, Maya Sánchez‐Baya, Jersy Cárdenas‐Salas, Blanca Timón‐Vázquez, Juan J. Gorgojo‐Martínez, Ines Modrego‐Pardo, Irea Fernández‐Xove, Jose Carlos Fernández‐García, Rebeca Reyes‐García   +13 more
wiley   +1 more source

FGF23: Is It Ready for Prime Time? [PDF]

Clinical Chemistry, 2011
Since the identification of fibroblast growth factor 23 (FGF23)2 more than a decade ago, interest in this hormone has grown dramatically among both nephrologists and endocrinologists. FGF23, initially identified in patients with rare forms of hypophosphatemia, is also increased in patients with chronic kidney disease (CKD).
openaire   +2 more sources

Tenapanor Beyond Phosphate: Gut Sodium Transport, Stool Transit Time, and Volume Balance in Dialysis Patients

Hemodialysis International, Volume 30, Issue 4, Page 689-697, October 2026.
ABSTRACT Introduction Tenapanor, a minimally absorbed intestinal NHE3 inhibitor approved for hyperphosphatemia in dialysis, lowers phosphate and reduces intestinal sodium absorption. Its sodium–water signal may have implications beyond phosphate but remains poorly separated from diarrhea‐mediated losses and dialysis prescription artifacts. Methods This
Lucas Maciel de Almeida Corrêa, Luiggi Kevin Virgino Brandão, Clara Belo Gamon Santiago, Alexandre de Assis Barbosa, Gabriel Rian Mazur, Gabriel Costa de Santana, Yan Roberth Delmiro Silva, Letícia Esteves Dante, Ivan Felipe Dutra Júnior   +8 more
wiley   +1 more source

Novel early markers of chronic kidney disease

Pediatria i Medycyna Rodzinna, 2019
Chronic kidney disease is an irreversible kidney damage caused by structural or functional renal impairment and persisting for more than 3 months. It is usually accompanied by albuminuria, proteinuria, abnormal histopathological and imaging findings as ...
Anna Bujnowska, Agata Będzichowska, Katarzyna Jobs, Bolesław Kalicki   +3 more
doaj   +1 more source

FGF23‐related hypophosphatemic rickets preceding the onset of systemic lupus erythematosus: A juvenile case

Clinical Case Reports
Key Clinical Message This case report describes the clinical course of a juvenile female with FGF23‐related hypophosphatemic rickets preceding the onset of SLE. Our study demonstrates the possibility of hypophosphatemic rickets as an early symptom of SLE.
Yoko tabei, Yoshiaki Ohtsu, Masaharu Shimada, Aya Wada, Emi Hamajima, Yoshimitsu Osawa, Takumi Takizawa   +6 more
doaj   +1 more source

IRF4/FGF23 in gingival crevicular fluid: Diagnostic biomarkers for Dentin Hypersensitivity [PDF]

Journal of Medical Biochemistry
Background: The aim of this study is to investigate the diagnostic value of interferon regulatory factor 4 (IRF4) and fibroblast growth factor 23 (FGF23) in gingival crevicular fluid (GCF) and serum for dentin hypersensitivity (DH), and to analyze the ...
Can Song, Yubao Jia, Yaxuan Liu, Yujie Zhang, Jing Yu, Mengmeng Xian   +5 more
doaj   +1 more source

FGF23 Producing Mesenchymal Tumor

Case Reports in Endocrinology, 2014
A 40-year-old patient was referred to Clinic of Endocrinology due to hypophosphatemia causing pain, cramps, and weakness of muscles. Moreover, his bone mineral density was very low. The previous treatment with phosphorus and active vitamin D metabolites was ineffective.
Lucyna Papierska, Jarosław B. Ćwikła, Waldemar Misiorowski, Michał Rabijewski, Krzysztof Sikora, Hubert Wanyura   +5 more
openaire   +3 more sources