Results 141 to 150 of about 2,012 (174)

Genomic complexity in advanced gastric and esophageal adenocarcinomas: a case report of rare <i>WDR11</i>-<i>AS1</i>-<i>FGFR2</i> fusions. [PDF]

Front Oncol
Mehlhaff E, Deming DA, Kratz JD, Obeidat K, Welch L, Uboha N.   +5 more
europepmc   +1 more source

Increased thermal stability of FGF10 leads to ectopic signaling during development. [PDF]

Cell Mol Life Sci
Czyrek AA, Baran K, Hruba E, Horackova A, Bosakova V, Chudzian J, Fafilek B, Laskova V, Stepankova V, Bednar D, Karl K, Kasparek P, Bosakova M, Killinger M, Szotkowska T, Prochazka J, Zieba JT, Rico-Llanos G, Fric J, Hadzic S, Loku E, Wujak M, Svozilova K, Stroblova M, Sedlacek R, Hristova K, Krakow D, Kubovciak J, Delattre M, Bartoszewski R, Buchtova M, Krowarsch D, Chaloupkova R, Zakrzewska M, Krejci P.   +34 more
europepmc   +1 more source

Precision oncology in gastric cancer: navigating molecular subtypes, therapeutic targets, and future horizons. [PDF]

Cell Oncol (Dordr)
Hong Y, Wang X, Yu H, Liu X, Tang C.
europepmc   +1 more source

Fibroblast growth factor-7 promotes repair of primary human bronchial epithelial cells

Quinn S, Jenkins A, Konstantinidi R, Molyneaux PL, Patel AK.   +4 more
europepmc   +1 more source

Fgfr2b Signaling Is Essential for the Maintenance of the Alveolar Epithelial Type 2 Lineage During Lung Homeostasis in Mice [PDF]

Cellular and Molecular Life Sciences, 2022
Fibroblast growth factor receptor 2b (Fgfr2b) signaling is essential throughout lung development to form the alveolar epithelial lineage. However, its role in alveolar epithelial type 2 cells (AT2s) homeostasis was recently considered dispensable.
Jochen Wilhelm, Saverio Bellusci, Susanne Herold   +2 more
exaly   +2 more sources

FGFR2b Signalling Restricts Lineage-Flexible Alveolar Progenitors During Mouse Lung Development and Converges in Mature Alveolar Type 2 Cells [PDF]

Cellular and Molecular Life Sciences, 2022
The specification, characterization, and fate of alveolar type 1 and type 2 (AT1 and AT2) progenitors during embryonic lung development are poorly defined.
Saverio Bellusci, Arun Lingampally, Jochen Wilhem   +2 more
exaly   +2 more sources

FGF10/FGFR2b Signaling Plays Essential Roles During in Vivo Embryonic Submandibular Salivary Gland Morphogenesis [PDF]

BMC Developmental Biology, 2005
Background: Analyses of Fgf10 and Fgfr2b mutant mice, as well as human studies, suggest that FGF10/FGFR2b signaling may play an essential, nonredundant role during embryonic SMG development. To address this question, we have analyzed the SMG phenotype in
Saverio Bellusci, Mohammad K Hajihosseini, Michael Melnick   +2 more
exaly   +2 more sources

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Fgf22 and Fgfr2b are required for neurogenesis and gliogenesis in the zebrafish forebrain

Biochemical and Biophysical Research Communications, 2023
Fibroblast growth factors (Fgfs) play crucial roles in various developmental processes including brain development. We previously identified Fgf22 in zebrafish and found that fgf22 is involved in midbrain patterning during embryogenesis. Here, we investigated the role of Fgf22 in the formation of the zebrafish forebrain.
Ayumi, Miyake, Takatoshi, Ohmori, Yuka, Murakawa   +2 more
openaire   +2 more sources

Phase I Escalation and Expansion Study of Bemarituzumab (FPA144) in Patients With Advanced Solid Tumors and FGFR2b-Selected Gastroesophageal Adenocarcinoma [PDF]

Journal of Clinical Oncology, 2020
Purpose: To evaluate the safety, pharmacokinetics, and preliminary activity of bemarituzumab in patients with FGFR2b-overexpressing gastric and gastroesophageal junction adenocarcinoma (GEA).
Hong Xiang, Daniel V T Catenacci, Sun Young Rha   +2 more
exaly   +4 more sources