Mass spec analysis identifies FGFR3 as binding partner of TAK1.
Mass spectrometry analysis of TAK1 immune complexes prepared from HEK293 cells identifies FGFR3 as a binding partner. The table shows recovered FGFR3 peptides (IPI Protein Index Identifier: IPI00027174,IPI00220253).
Matthew Hallowell (513742) +8 more
core +1 more source
SADDAN-FGFR3 signalling involves paxillin phosphorylation and causes cytoskeleton disorganization.
Mutations in the fibroblast growth factor receptor 3 (FGFR3) gene cause chondrodysplasias. FGFR3 is a tyrosine kinase (TK) receptor playing a key role in skeletal development as a negative regulator of bone growth.
Montone, Rosa +4 more
core +1 more source
Dkk1 inhibition restores mandibular growth in an achondroplasia mouse model
Briantana Raveendranathan +10 more
doaj +1 more source
Paired Urinary Cytology and Targeted FGFR3 S249C/R248C Mutation Detection in Urine from Patients with Bladder Cancer: A Pilot Study. [PDF]
Tichil BP +5 more
europepmc +1 more source
From FGFR3 Hyperactivation to Disease-Modifying Therapy in Pediatric Achondroplasia: Molecular Mechanisms, Clinical Evidence, and Emerging Treatments. [PDF]
Șerban RC +10 more
europepmc +1 more source
Iron Oxide Nanozyme for Magnetothermal Activation of ER-TRPV1 Enables Efficient Intravesical Therapy of Bladder Cancer. [PDF]
Li G +7 more
europepmc +1 more source
Case Report: Proportionate short stature in a three-generation family harboring <i>FGFR3</i> N540S: phenotypic expansion beyond hypochondroplasia and implications for genetic screening in idiopathic short stature. [PDF]
Zhang B, Wang X, Luo J, Gong C.
europepmc +1 more source
Fgfr3-Wnt signaling crosstalk is involved in maintaining cranial suture integrity. [PDF]
Pereur R +9 more
europepmc +1 more source
Integrating Molecular Classification Based on FGFR3, KRAS, HRAS, and TP53 Mutation With TNM Staging Modestly Improves Prediction of Prognosis of Upper Tract Urothelial Carcinoma After Surgery. [PDF]
Yanagida K +9 more
europepmc +1 more source
Development and Broad Application of a Double Drop-Off ddPCR Assay for Simultaneous Detection of Four <i>FGFR3</i> Mutations in Tissue and Liquid Biopsy Samples. [PDF]
Thanou E +9 more
europepmc +1 more source

