Results 41 to 50 of about 4,653 (185)

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

ASPEK PERLINDUNGAN MASYARAKAT SEBAGAI SARANA KEEFEKTIFAN SANKSI PIDANA BAGI PELAKU USAHA DI BIDANG METROLOGI LEGAL

Masalah-Masalah Hukum, 2022
Undang-Undang Nomor 2 Tahun 1981 tentang Metrologi Legal dimana pelakunya adalah pelaku usaha yang dengan sengaja melakukan perbuatan curang dalam alat ukur/takar/timbang dan perlengkapannya. Metode yang digunakan adalah penelitian hukum yuridis empiris.
Wenny Megawati, Rochmani Rochmani, Dian Ratu Ayu Uswatun Khasanah   +2 more
doaj   +1 more source

Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target

Advanced Science, EarlyView.
Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen, Pingmei Huang, Ruizhi Tao, Fenfen Ji, Qinyao Wei, Lok Hin Ko, Lianxin Zhou, Huarong Chen, Alvin Cheung, Wei Kang, Ko Fai To, Jun Yu, Chi Chun Wong   +12 more
wiley   +1 more source

Light‐Induced Phase Segregation in Mixed‐Halide Perovskites: Reconciling Mechanistic and Thermodynamic Models

Advanced Energy Materials, EarlyView.
Light‐induced halide segregation limits the stability of mixed‐halide perovskites. This perspective shows how different mechanistic models can be viewed within a common free‐energy framework. It highlights the need to separate kinetic and thermodynamic aspects, the need for bulk‐sensitive measurements, and the need for controlled conditions to identify
Markus Griesbach, Fatemeh Haddadi Barzoki, Anna Köhler, Helen Grüninger   +3 more
wiley   +1 more source

Overexpression of Nepenthesin HvNEP-1 in Barley Endosperm Reduces Fusarium Head Blight and Mycotoxin Accumulation

Agronomy, 2020
Fusarium head blight (FHB) causes substantial losses of yield and quality in grains, both in the field and in post-harvest storage. To date, adequate natural genetic resistance is not available for the control of FHB.
Zelalem Eshetu Bekalu, Claus Krogh Madsen, Giuseppe Dionisio, Inger Bæksted Holme, Lise Nistrup Jørgensen, Inge S. Fomsgaard, Henrik Brinch-Pedersen   +6 more
doaj   +1 more source

Infection mechanisms of Rhizoctonia cerealis in wheat

iMeta, EarlyView.
We discover that R. cerealis (Rc) is a primary pathogen causing sharp eyespot of wheat after 335 distinct isolates were isolated from 1683 SE‐diseased wheat plants across China over 7 years using a single hyphal tip isolation method. We then generated high‐quality reference genomes via de novo sequencing of five representative Rc isolates and ...
Yan Ren, Ti Liu, Heying Zhao, Qirun Qian, Lufei Cui, Zhipeng Sun, Wenkai Yang, Peng Guo, Sisheng Wang, Lingran Zhang, Congwei Sun, Aolin Jia, Ning Zhang, Feng Chen   +13 more
wiley   +1 more source

Separation of trichothecene mycotoxins in a matrix of hemp (Cannabis sativa L.) seed, and quantification of deoxynivalenol in hemp grain infected with Fusarium graminearum

JSFA reports, EarlyView.
Abstract Background Fusarium graminearum, one of the causal agents of ear rot in maize and head blight of cereal grains, also infects hemp (Cannabis sativa L. containing a maximum of 0.3% tetrahydrocannabinol or THC). This fungal pathogen produces trichothecene mycotoxins when it infects maize and cereal grains, but little is known about its production
Isabelle A. Kagan, Magdalena Ricciardi, Henry S. Smith, Rachel R. Schendel, Robert Pearce, Nicole Gauthier   +5 more
wiley   +1 more source

VALIDAÇÃO DA CONTAGEM MANUAL DE HEMÁCIAS, LEUCÓCITOS E PLAQUETAS

Hematology, Transfusion and Cell Therapy
A validação de metodologias e processos deve ser realizada pelo serviço de hemoterapia para demonstrar que seus resultados são confiáveis e atendem aos atributos de qualidade definidos nas normativas que regem o Ciclo do Sangue.
LM Araújo, VB Lima, AC Fernandes, JPO Rosa, EJD Silva, JS Ribeiro, PF Araújo, CB Lima, JA Lima, MM Coelho   +9 more
doaj   +1 more source

Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan, Bei Huang, Siyi Gong, Yuhua Yang, Shi Tang, Steven Wai‐ho Chau, Ngan Yin Chan, Tim Man‐ho Li, Yaping Liu, Anne Y.Y. Chan, Karen K.Y. Ma, Shirley X. Li, Joshua Tsoh, Kelvin K.L. Chong, Kathryn A. Roecklein, Vincent C.T. Mok, Yun Kwok Wing   +16 more
wiley   +1 more source

Understanding the Meaning of a Good Death for People Living With Parkinson's Disease: Qualitative Study

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Parkinson's disease is the second most common neurodegenerative disorder globally. Despite growing attention to palliative care in Parkinson's disease, little is known about what constitutes a “good death” from the perspective of people living with Parkinson's disease (PLwPD).
Leonardo Martins, Rasa Mikelyte, Ricardo Silva Carvalho, Henrique Ballalai Ferraz, Déborah Oliveira, Julia Maria Vanelli, Natália Rocha Tardelli, Fernanda Bono Fukushima, Edison Iglesias de Oliveira Vidal   +8 more
wiley   +1 more source