Results 61 to 70 of about 842,620 (308)

Evaluation of fiber reinforcement on the strength behaviors of dredging slurry cemented at high water content

Soils and Foundations, 2023
This study evaluates the strength behaviors of dredging slurry at high water content reinforced by polypropene fibers. Variables, including cement content, curing time, fiber content, fiber length, and water content, were applied to study the effects on ...
Guizhong Xu, Qiyuan Han, Weijuan Geng, Jie Yin, Lin Liu   +4 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Deficiency of dietary fiber in Slc5a8-null mice promotes bacterial dysbiosis and alters colonic epithelial transcriptome towards proinflammatory milieu [PDF]

, 2019
Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the intestinal tract due to disruption of the symbiotic relationship between the host immune system and microbiota.
Elmassry, Moamen, Faruk Sikder, Mohd Omar, Ganapathy, Pramodh K., Ganapathy, Vadivel, Kottapalli, Kameswara Rao, Ramachandran, Sabarish, Sivaprakasam, Sathish   +6 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Research on Dynamic Mechanical Properties and Constitutive Model of Basalt Fiber Reinforced Concrete after Exposure to Elevated Temperatures under Impact Loading

Applied Sciences, 2020
The dynamic mechanical properties of basalt fiber reinforced concrete (BFRC) with different fiber contents (0.0%, 0.1%, 0.2%, 0.3%, 0.4%), confining pressures (0 MPa, 5 MPa, 10 MPa, 15 MPa) and exposed to different temperatures (20 °C, 200 °C, 400 °C ...
Wenbiao Liang, Junhai Zhao, Yan Li, Yue Zhai, Zhou Wang, Yubing Yang   +5 more
doaj   +1 more source

Human skeletal muscle fiber type specific protein content [PDF]

Analytical Biochemistry, 2012
The aim of this project was to develop a method to assess fiber type specific protein content across the continuum of human skeletal muscle fibers. Individual vastus lateralis muscle fibers (n = 264) were clipped into two portions: one for sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) fiber typing and one for Western blot protein
Andrew J, Galpin, Ulrika, Raue, Bozena, Jemiolo, Todd A, Trappe, Matthew P, Harber, Kiril, Minchev, Scott, Trappe   +6 more
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Nutritional characteristics of selected insects in Uganda for use as alternative protein sources in food and feed [PDF]

, 2020
Open Access Journal; Published online: 18 Dec 2019Insects are potential ingredients for animal feed and human food. Their suitability may be influenced by species and nutritional value.
Bbosa, T., Fiaboe, K.K.M., Mukisa, I.M., Nakimbugwe, D., Ndagire, C.T.   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study of PVA fibers to improve the corrosion resistance of Suzhou Typical River Mucky Clay

AIMS Environmental Science
To investigate the effect of Polyvinyl Alcohol (PVA) fiber incorporation on the erosion resistance of soil under different environmental conditions, this study selected fiber length and fiber content as variables and systematically compared the ...
Yuexiang Wang, Haigao Jia, Kaiyu Chen
doaj   +1 more source