Results 21 to 30 of about 601,314 (362)

YKL-40 is highly expressed in the epicardial adipose tissue of patients with atrial fibrillation and associated with atrial fibrosis

Journal of Translational Medicine, 2018
Background YKL-40 (CHI3L1) is a novel biomarker for inflammation, tissue remodeling, and fibrosis, as well as cardiovascular diseases. We investigated the association between YKL-40 expression in epicardial adipose tissue (EAT) and atrial fibrosis in ...
Qing Wang, Hua Shen, Jie Min, Yang Gao, Kai Liu, Wang Xi, Jie Yang, Liang Yin, Jibin Xu, Jian Xiao, Zhinong Wang   +10 more
doaj   +1 more source

A resorcinarene for inhibition of Aβ fibrillation. [PDF]

, 2017
Amyloid-β peptides (Aβ) fibrillation is the hallmark of Alzheimer's disease (AD). However, it has been challenging to discover potent agents in order to inhibit Aβ fibrillation.
Han, Xu, Houk, KN, Leblanc, Roger M, Malagon, Andres, Park, Jiyong, Vargas, Edgar, Wang, Lingyu, Wikramanayake, Athula, Wu, Wei   +8 more
core   +1 more source

Physiological Assessment of Ventricular Myocardial Voltage Using Omnipolar Electrograms

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundCharacterization of myocardial health by bipolar electrograms are critical for ventricular tachycardia therapy. Dependence of bipolar electrograms on electrode orientation may reduce reliability of voltage assessment along the plane of ...
Karl Magtibay, Stéphane Massé, John Asta, Marjan Kusha, Patrick F. H. Lai, Mohammed Ali Azam, Andreu Porta‐Sanchez, Shouvik Haldar, Daniel Malebranche, Christopher Labos, D. Curtis Deno, Kumaraswamy Nanthakumar   +11 more
doaj   +1 more source

Blood pressure control versus atrial fibrillation management in stroke prevention [PDF]

, 2015
Hypertension is one of the major risk factors for atrial fibrillation which in turn is the most prevalent concomitant condition in hypertensive patients. While both these pathological conditions are independent risk factors for stroke, the association of
Sada, Lidia, Savoia, Carmine, Volpe, Massimo   +2 more
core   +1 more source

Incidence and Predictors of Complications During Cryoballoon Pulmonary Vein Isolation for Atrial Fibrillation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCryoballoon pulmonary vein isolation (PVI) has emerged as an alternative to radiofrequency PVI for atrial fibrillation (AF). Data are lacking to define the rates and predictors of complications, particularly phrenic nerve injury (PNI).
Emily N. Guhl, Donald Siddoway, Evan Adelstein, Raveen Bazaz, George S. Mendenhall, Jan Nemec, Samir Saba, David Schwartzman, Andrew Voigt, Norman C. Wang, Sandeep K. Jain   +10 more
doaj   +1 more source

Non-equilibrium Growth and Twist of Cross-Linked Collagen Fibrils [PDF]

, 2020
The lysyl oxidase (LOX) enzyme that catalyses cross-link formation during the assembly of collagen fibrils in vivo is too large to diffuse within assembled fibrils, and so is incompatible with a fully equilibrium mechanism for fibril formation. We propose that enzymatic cross-links are formed at the fibril surface during the growth of collagen fibrils;
arxiv   +1 more source

Focal impulse and rotor modulation of atrial rotors during atrial fibrillation leads to organization of left atrial activation as reflected by waveform morphology recurrence quantification analysis and organizational index

Journal of Arrhythmia, 2020
Background Focal impulse and rotor modulation (FIRM) can cause slowing, organization, and occasionally termination of atrial fibrillation (AF), although results have been mixed.
Peter R. Liu, Daniel J. Friedman, Adam S. Barnett, Kevin P. Jackson, James P. Daubert, Jonathan P. Piccini   +5 more
doaj   +1 more source

Uniform spatial distribution of collagen fibril radii within tendon implies local activation of pC-collagen at individual fibrils [PDF]

Physical Biology, v. 13 (2016) 046008, 2016
Collagen fibril cross-sectional radii show no systematic variation between the interior and the periphery of fibril bundles, indicating an effectively constant rate of collagen incorporation into fibrils throughout the bundle. Such spatially homogeneous incorporation constrains the extracellular diffusion of collagen precursors from sources at the ...
arxiv   +1 more source

Amyloid fibril formation kinetics of low-pH denatured bovine PI3K-SH3 monitored by three different NMR techniques

Frontiers in Molecular Biosciences, 2023
Introduction: Misfolding of amyloidogenic proteins is a molecular hallmark of neurodegenerative diseases in humans. A detailed understanding of the underlying molecular mechanisms is mandatory for developing innovative therapeutic approaches.
Luis Gardon, Luis Gardon, Nina Becker, Nina Becker, Nick Rähse, Christoph Hölbling, Athina Apostolidis, Celina M. Schulz, Kevin Bochinsky, Lothar Gremer, Lothar Gremer, Henrike Heise, Henrike Heise, Nils-Alexander Lakomek, Nils-Alexander Lakomek   +14 more
doaj   +1 more source

Temperature diagnostics of chromospheric fibrils [PDF]

A&A 672, A89 (2023), 2023
Context. Chromospheric fibrils are thin and elongated structures that connect nearby photospheric magnetic field concentrations of opposite polarities. Aims. We assess the possibilities and drawbacks related to the use of current instrumentation and inversion techniques to infer the thermodynamic structure of chromospheric fibrils. Methods. We employed
arxiv   +1 more source