Results 111 to 120 of about 23,678,950 (225)

New insights into the structural role of EMILINs within the human skin microenvironment

Scientific Reports
Supramolecular extracellular matrix (ECM) networks play an essential role in skin architecture and function. Elastin microfibril interface-located proteins (EMILINs) comprise a family of three extracellular glycoproteins that serve as essential ...
Alvise Schiavinato, Fady Marcous, Alexandra V. Zuk, Douglas R. Keene, Sara F. Tufa, Laura M. Mosquera, Paola Zigrino, Cornelia Mauch, Beate Eckes, Katrien Francois, Julie De Backer, Nicolas Hunzelmann, Pia Moinzadeh, Thomas Krieg, Bert Callewaert, Gerhard Sengle   +15 more
doaj   +1 more source

Microfibril-associated Glycoprotein-2 (MAGP-2) Is Specifically Associated with Fibrillin-containing Microfibrils but Exhibits More Restricted Patterns of Tissue Localization and Developmental Expression Than Its Structural Relative MAGP-1 [PDF]

, 1998
Mark A. Gibson, Merran Finnis, Jaliya Kumaratilake, Edward G. Cleary   +3 more
openalex   +1 more source

Structure of the Mutant Fibrillin-1 Gene in the Tight Skin (TSK) Mouse [PDF]

, 1997
C Bona
openalex   +1 more source

A novel fibrillin-1 gene missense mutation associated with neonatal Marfan syndrome: a case report and review of the mutation spectrum

BMC Pediatrics, 2016
BackgroundMarfan syndrome (MFS) is a heritable disorder of connective tissue resulting from pathogenic variants of the fibrillin-1 gene (FBN1). Neonatal Marfan syndrome (nMFS) is rare and the most severe form of MFS, involving rapidly progressive ...
Qian Peng, Yan Deng, Yuan Yang, Hanmin Liu   +3 more
semanticscholar   +1 more source

P1148A in fibrillin-1 is not a mutation anymore [PDF]

Nature Genetics, 1997
Mei Wang, Kurt R. Mathews, Bruce Blumberg, Soraya Beiraghi, John M. Graham, Kiyoshi Imaizumi, Maurice Godfrey, Maren T. Scheuner   +7 more
openaire   +3 more sources

The Microfibrillar Proteins MAGP-1 and Fibrillin-1 Form a Ternary Complex with the Chondroitin Sulfate Proteoglycan Decorin [PDF]

, 2000
Barbara Crippes Trask, Timothy M. Trask, Thomas J. Broekelmann, Robert P. Mecham   +3 more
openalex   +1 more source

Mutations in Calcium-binding Epidermal Growth Factor Modules Render Fibrillin-1 Susceptible to Proteolysis [PDF]

, 2000
Dieter P. Reinhardt, Robert N. Ono, Holger Notbohm, Peter Müller, Hans Peter Bächinger, Lynn Y. Sakai   +5 more
openalex   +1 more source

Fibrillin-1 (FBN-1) a new marker of germ cell neoplasia in situ

BMC Cancer, 2016
BackgroundGerm cell neoplasia in situ (GCNIS), is preinvasive stage of testicular germ cell tumours (TGCTs). Fibrillins, which are integral components of microfibrils are suggested to be involved in cancer pathogenesis and maintenance of embryonic stem ...
Z. Cierna, M. Mego, I. Jurisica, K. Macháleková, M. Chovanec, V. Miskovska, D. Světlovská, K. Kalavska, K. Rejlekova, K. Kajo, J. Mardiak, P. Babál   +11 more
semanticscholar   +1 more source

The Biomechanics of Fibrillin Microfibrils: Lessons from the Ciliary Zonule

Cells
Marfan syndrome is an inherited connective tissue disorder that affects the cardiovascular, musculoskeletal, and ocular systems. It is caused by pathogenic variants in the fibrillin-1 gene (FBN1).
Pooja Rathaur, Juan Rodriguez, John Kuchtey, Samuel Insignares, Wendell B. Jones, Rachel W. Kuchtey, Steven Bassnett   +6 more
doaj   +1 more source

Anti-Glycation Activities of Phenolic Constituents from Silybum marianum (Milk Thistle) Flower in Vitro and on Human Explants

Molecules, 2015
Glycation is an ageing reaction of naturally occurring sugars with dermal proteins, with clinical signs appearing in vivo around age 30, and increasing steadily/regularly with age.
Seoungwoo Shin, Jung-A Lee, Minkyung Kim, Hyunwoo Kum, Eunsun Jung, Deokhoon Park   +5 more
doaj   +1 more source