Results 101 to 110 of about 22,293 (293)
BMC Cardiovascular Disorders, 2020 Background Elderly patients have a relatively high cardiovascular risk due to increased arterial stiffness, elevated blood pressure and decreased amounts of elastin in the arteries.
Ida Åström Malm +4 more
doaj +1 more source
Congenital ectopia lentis : diagnosis and treatment [PDF]
, 2012 Congenital ectopia lentis (EL) is an ocular condition, which typically causes a high grade of refractive errors, mainly myopia and astigmatism. These might be difficult to compensate for, especially in children, who might develop ametropic amblyopia ...
Rysä Konradsen, Tiina
core +1 more source
Advanced Science, Volume 12, Issue 21, June 5, 2025.Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu +13 more
wiley +1 more source
Fibrillin–integrin interactions in health and disease
Biochemical Society Transactions, 2008 Human fibrillin-1 is the major structural protein of extracellular matrix 10–12 nm microfibrils. It has a disulfide-rich modular organization which consists primarily of cbEGF (Ca2+-binding epidermal growth factor-like) domains and TB (transforming growth factor β-binding protein-like) domains.
Jovanovic, J +4 more
openaire +5 more sources
Histopathology of aortic complications in bicuspid aortic valve versus Marfan syndrome: relevance for therapy? [PDF]
, 2016 Patients with bicuspid aortic valve (BAV) and patients with Marfan syndrome (MFS) are more prone to develop aortic dilation and dissection compared to persons with a tricuspid aortic valve (TAV).
Bogers, A.J.J.C. (Ad) +10 more
core +1 more source
Antioxidant Natural Plant Constituents for Diabetic Wound Repair
MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.Antioxidant natural plant constituents promote diabetic wound repair by ameliorating oxidative stress, inhibiting inflammatory responses, and promoting tissue regeneration. ABSTRACT Diabetes mellitus is a prevalent metabolic disorder characterized by a prolonged hyperglycemic state, which can result in complications affecting multiple organ systems ...
Lele Meng +3 more
wiley +1 more source
Plants, 2018 Fibrillin (FBN) is a plastid lipid-associated protein found in photosynthetic organisms from cyanobacteria to plants. In this study, 10 CsaFBN genes were identified in genomic DNA sequences of cucumber (Chinese long and Gy14) through database searches ...
Inyoung Kim +5 more
doaj +1 more source
Frontiers in Genetics, 2021 The term “fibrillinopathies” gathers various diseases with a wide spectrum of clinical features and severity but all share mutations in the fibrillin genes.
Pauline Arnaud +5 more
doaj +1 more source
Proteomic analysis of the bovine and human ciliary zonule [PDF]
, 2016 PURPOSE: The zonule of Zinn (ciliary zonule) is a system of fibers that centers the crystalline lens on the optical axis of the eye. Mutations in zonule components underlie syndromic conditions associated with a broad range of ocular pathologies ...
Bassnett, Steven +3 more
core +2 more sources
Fiber Type‐Specific Proteomic Alterations in R349P Desminopathy Mice
Muscle &Nerve, Volume 71, Issue 6, Page 1113-1121, June 2025.ABSTRACT Introduction/Aims Desminopathies are a group of rare human myopathies and cardiomyopathies caused by pathogenic variants of the desmin gene. Here, we analyzed the effects of the R349P mutant desmin on the proteomic profiles of individual fiber types of murine skeletal muscle.
Britta Eggers +7 more
wiley +1 more source