Results 91 to 100 of about 12,218 (212)

Low‐Dose H2O2 Priming Improves Performance Under Simulated Marine Heatwave Conditions in a Coastal Bivalve

Global Challenges, Volume 10, Issue 6, June 2026.
Low‐dose hydrogen peroxide priming shapes Manila clam responses to simulated marine heatwaves, which showed faster burrowing behavior, limited transcriptional disruption, and reduced opportunistic microbiota. A long‐term field trial confirms no detectable adverse effects, supporting redox‐based chemical priming as a feasible resilience strategy in ...
Chiara Mascitelli, Giovanna Monticelli, Alessandro Nardi, Giulia Dalla Rovere, Graziano Rilievo, Ilaria Bernardini, Nicole Macrì, Deborah Cesaroni, Valentina Tavolazzi, Gabriele Andreatta, Tomaso Patarnello, Luca Bargelloni, Luca Peruzza, Maura Benedetti, Massimo Milan   +14 more
wiley   +1 more source

Fibrillin-1 expression in normal and fibrotic rat liver and in cultured hepatic fibroblastic cells: modulation by mechanical stress and role in cell adhesion

, 2004
Fibrillin-1, together with elastin, is the main component of elastic fibers found throughout the extracellular space and responsible for the biomechanical properties of most tissues and organs.
Vincent Sapin (149436), Alexis Desmouliere (19972701), Jean Rosenbaum (724183), Dieter Reinhardt (10077097), Dionne Lorena (20007603), Ian Darby (4433218)   +5 more
core  

Homotypic fibrillin-1 interactions in microfibril assembly

, 2005
We have defined the homotypic interactions of fibrillin-1 to obtain new insights into microfibril assembly. Dose-dependent saturable high affinity binding was demonstrated between N-terminal fragments, between furin processed C-terminal fragments, and ...
Mellody, Kieran, Marson, Andrew, Kielty, Cay M., Rock, Matthew J., Cain, Stuart A.; id_orcid, Morgan, Amanda, Baldock, Clair, Freeman, Lyle J., Shuttleworth, C. Adrian   +8 more
core   +1 more source

Gastric Cancer: Pathobiology and Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
Gastric cancer is a multistep process driven by the interplay of microbial virulence, host epithelial injury, and evolving molecular reprogramming. Initiation involves pathogen‐induced epigenetic alterations and the early subversion of key oncogenic signaling networks, facilitating the transition from chronic injury to metaplasia and malignant ...
Ruixian Yu, Miao Zhang, Yan Meng, Chunxiao Zhu, Weihong Zhang, Hui Zhang, Zhifa Cao, Meihang Du, Zhangting Zhao, Junping Bai, Yi Han, Yang Tang, Wei Kang, Ka Fai To, Shi Jiao, Liwei An, Zhaocai Zhou   +16 more
wiley   +1 more source

The hidden science of haptics: A pedagogical review of tactile evaluation in cosmetics

International Journal of Cosmetic Science, Volume 48, Issue 3, Page 600-634, June 2026.
This review explores the physiological basis of tactile perception and critically examines classical and emerging sensory methods used in cosmetics, advocating for broader methodological integration and recognition of sensory analysis in the field. Abstract Sensory analysis is a cornerstone of cosmetic development, yet remains underrepresented in peer ...
Morgane Postec, Daria Terescenco, Ecaterina Gore   +2 more
wiley   +1 more source

Human eye development is characterized by coordinated expression of fibrillin isoforms

, 2022
S.7934-7944Purpose: Mutations in human fibrillin-1 and -2, which are major constituents of tissue microfibrils, can affect multiple ocular components, including the ciliary zonule, lens, drainage apparatus, cornea, and retina.
Plesec, T., Schenke-Layland, Katja, Hubmacher, D., Apte, S.S., Reinhardt, D.P.   +4 more
core   +1 more source

ADAR1 Is Essential for Smooth Muscle Homeostasis and Vascular Integrity

Cells
Vascular smooth muscle cells (VSMCs) play a critical role in maintaining vascular integrity. VSMC dysfunction leads to numerous vascular diseases. Adenosine deaminases acting on RNA 1 (ADAR1), an RNA editing enzyme, has shown both RNA editing and non ...
Dunpeng Cai, Shi-You Chen
doaj   +1 more source

Persistent great artery dilatation in Beals syndrome: A novel finding

Annals of Pediatric Cardiology, 2019
We report a unique case of dilated aortic root and pulmonary artery in an infant with clinical features consistent with Beals syndrome confirmed to have fibrillin-2 mutation.
Saira Siddiqui, Laurie Panesar
doaj   +1 more source

Mechanistic Review of Topical Therapies Targeting Dermal Fibroblasts in Skin Aging and Rejuvenation

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Skin aging appears in multiple forms, including wrinkles, sagging, scarring, atrophy, and photoaging. Although each phenotype has distinct biological features, all are rooted in dermal fibroblast dysfunction. This review examines the molecular pathways underlying these conditions and evaluates topical interventions designed to ...
Seyedeh Melika Akaberi, Mohammad Esfandiyari, Hamid Reza Ahmadi Ashtiani   +2 more
wiley   +1 more source

ADAMTSL6β Protein Rescues Fibrillin-1 Microfibril Disorder in a Marfan Syndrome Mouse Model through the Promotion of Fibrillin-1 Assembly [PDF]

This research was originally published in the Journal of Biological Chemistry. Masahiro Saito, Misaki Kurokawa, Masahito Oda, Masamitsu Oshima, Ko Tsutsui, Kazutaka Kosaka, Kazuhisa Nakao, Miho Ogawa, Ri-ichiroh Manabe, Naoto Suda, Ganburged Ganjargal ...
Ganjargal, Ganburged, Manabe, Ri-ichiroh, Oshima, Masamitsu, Tsutsui, Ko, Tsuji, Takashi, Nakao, Kazuhisa, Sekiguchi, Kiyotoshi, Teranaka, Toshio, Kurokawa, Misaki, Noguchi, Toshihide, Suda, Naoto, Hada, Yasunobu, Saito, Masahiro, Kosaka, Kazutaka, Ogawa, Miho, Yoneda, Toshiyuki, Oda, Masahito   +16 more
core   +1 more source