Results 141 to 150 of about 10,219 (178)
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2018
Fibrillins are one of the major components of supramolecular fibrous structures in the extracellular matrix of elastic and nonelastic tissues, termed microfibrils. Microfibrils provide tensile strength in nonelastic tissues and scaffolds for the assembly of tropoelastin in elastic tissues, and act a regulator of growth factor bioavailability and ...
Heena, Kumra, Dieter P, Reinhardt
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Fibrillins are one of the major components of supramolecular fibrous structures in the extracellular matrix of elastic and nonelastic tissues, termed microfibrils. Microfibrils provide tensile strength in nonelastic tissues and scaffolds for the assembly of tropoelastin in elastic tissues, and act a regulator of growth factor bioavailability and ...
Heena, Kumra, Dieter P, Reinhardt
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2005
Fibrillin microfibrils are widely distributed extracellular matrix assemblies that endow elastic and nonelastic connective tissues with long-range elasticity. They direct tropoelastin deposition during elastic fibrillogenesis and form an outer mantle for mature elastic fibers.
Kielty, Cay M. +3 more
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Fibrillin microfibrils are widely distributed extracellular matrix assemblies that endow elastic and nonelastic connective tissues with long-range elasticity. They direct tropoelastin deposition during elastic fibrillogenesis and form an outer mantle for mature elastic fibers.
Kielty, Cay M. +3 more
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Immunohistochemical expression of fibrillin‐1 and fibrillin‐2 during tooth development
Journal of Periodontal Research, 2014Background and ObjectiveOxytalan fibers are categorized as a microfibril assembly without elastin deposition, and are unique components in the periodontal ligament (PDL). However, little is known about their formation during PDL development. To clarify the mechanisms of oxytalan fiber formation in developing PDL, we performed immunohistochemical ...
M, Kira-Tatsuoka +4 more
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The fibrillin‐marfan syndrome connection
BioEssays, 1993AbstractA few years ago no one would have suspected that the well‐known disorder of connective tissue, Marfan syndrome, could be caused by mutations in a recently discovered extracellular component, fibrillin. Likewise, nobody would have predicted that fibrillin represents a small family of proteins that are associated with several pheno‐typically ...
F, Ramirez, L, Pereira, H, Zhang, B, Lee
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Fibrillin immunofluorescence in pseudoxanthoma elasticum
Journal of the American Academy of Dermatology, 1995Pseudoxanthoma elasticum (PXE) is a rare heritable connective tissue disorder manifested by skin, ocular, and cardiovascular anomalies. The basic defect is unknown; however, the microscopic findings are indicative of defects in elastic fibers. Among the components of the elastic fibers are elastin and elastin-associated microfibrils.We assessed the ...
M, Godfrey +6 more
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2010
Microfibrils are supramolecular structures ubiquitously found in the extracellular matrix of elastic and nonelastic tissues. The three members of the cysteine-rich fibrillin family constitute the core of microfibrils. Mutations in fibrillin-1 and -2 lead to a number of heritable connective tissue disorders termed fibrillinopathies.
Dirk Hubmacher, Dieter P. Reinhardt
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Microfibrils are supramolecular structures ubiquitously found in the extracellular matrix of elastic and nonelastic tissues. The three members of the cysteine-rich fibrillin family constitute the core of microfibrils. Mutations in fibrillin-1 and -2 lead to a number of heritable connective tissue disorders termed fibrillinopathies.
Dirk Hubmacher, Dieter P. Reinhardt
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Journal of Dental Research, 2002
The elastic system fibers consist of three types—oxytalan, elaunin, and elastic fibers—differing in their relative microfibril and elastin contents. All three types are found in human gingiva, but human periodontal ligaments contain only elastin-free fibers.
E, Tsuruga, K, Irie, T, Yajima
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The elastic system fibers consist of three types—oxytalan, elaunin, and elastic fibers—differing in their relative microfibril and elastin contents. All three types are found in human gingiva, but human periodontal ligaments contain only elastin-free fibers.
E, Tsuruga, K, Irie, T, Yajima
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Organization and Biomechanical Properties of Fibrillin Microfibrils
2004The evolution and function of multicellular organisms has required tissue flexibility and the necessity to withstand stretch. These properties underpin movement and allow responses to changing environments. The elastic fibre is a bio-composite material composed of two insoluble extracellular matrix assemblies; fibrillin-rich microfibrils and elastin ...
Kielty, C M +5 more
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Abnormalities of fibrillin in acquired cutis laxa
Journal of the American Academy of Dermatology, 1994Degeneration of elastic tissue in acquired cutis laxa has been previously described, but microfibrils have not been adequately studied.We determined whether the microfibrillar component of elastic tissue is affected in skin of a patient with acquired cutis laxa.Lesional skin was examined with indirect immunofluorescence and immunoelectron microscopy ...
M G, Lebwohl +5 more
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