Results 61 to 70 of about 10,219 (178)

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

open access: yesPhotodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
ABSTRACT Background/Purpose Visible light (VL), and particularly high‐energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes.
Azahara Rodríguez‐Luna   +5 more
wiley   +1 more source

DNA DIAGNOSTICS AND MUTATION SPECTRUM OF THE GENE FBN1 IN MARFAN’S SYNDROME

open access: yesРоссийский кардиологический журнал, 2015
Aim. The development of an optimal protocol for diagnostic search for mutations with the use of the new generation sequencing technique (NGS) and evaluation of the mutation spectrum in Russian selection of the patients with Marfan syndrome.Material and ...
Yu. A. Rogozhina   +3 more
doaj   +1 more source

Fibrillin–integrin interactions in health and disease

open access: yesBiochemical Society Transactions, 2008
Human fibrillin-1 is the major structural protein of extracellular matrix 10–12 nm microfibrils. It has a disulfide-rich modular organization which consists primarily of cbEGF (Ca2+-binding epidermal growth factor-like) domains and TB (transforming growth factor β-binding protein-like) domains.
Jovanovic, J   +4 more
openaire   +4 more sources

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

open access: yesAdvanced Science, Volume 13, Issue 38, 9 July 2026.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong   +4 more
wiley   +1 more source

Thoracic Aortic Dissection in a Patient With Classical Homocystinuria: Implications for Aortic Surveillance

open access: yesJIMD Reports, Volume 67, Issue 4, July 2026.
ABSTRACT Classical homocystinuria (OMIM #236300), a rare inherited metabolic disorder caused by cystathionine beta‐synthase (CBS) deficiency, is characterized by markedly elevated homocysteine levels and associated multisystem complications. While the role of homocystinuria in venous thromboembolism is well recognized, there is limited evidence of ...
Marisa Chard   +2 more
wiley   +1 more source

Phosphate overload via the type III Na-dependent Pi transporter represses aortic wall elastic fiber formation

open access: yesFujita Medical Journal
Objectives: Phosphate (Pi) induces differentiation of arterial smooth muscle cells to the osteoblastic phenotype by inducing the type III Na-dependent Pi transporter Pit-1/solute carrier family member 1.
Yasumasa Yoshino   +13 more
doaj   +1 more source

Pathogenic Mechanisms of Bicuspid Aortic Valve Aortopathy

open access: yesFrontiers in Physiology, 2017
Bicuspid aortic valve (BAV) is the most common congenital valvular defect and is associated with ascending aortic dilation (AAD) in a quarter of patients. AAD has been ascribed both to the hemodynamic consequences of normally functioning and abnormal BAV
Noor M. Yassine   +2 more
doaj   +1 more source

The role of calcium in the organization of fibrillin microfibrils

open access: yesFEBS Letters, 1993
The microfibrillar glycoprotein fibrillin has a multidomain structure which contains forty‐three epidermal growth factor‐like motifs with calciumbinding consensus sequences. We have utilized intact microfibrils isolated from human dermal fibroblast cultures to investigate the putative influence of bound calcium on microfibrillar organization and ...
Kielty, CM, Shuttleworth, CA
openaire   +3 more sources

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3788-3813, July 2026.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Genome-Wide Identification and Expression Analyses of the Fibrillin Family Genes Suggest Their Involvement in Photoprotection in Cucumber

open access: yesPlants, 2018
Fibrillin (FBN) is a plastid lipid-associated protein found in photosynthetic organisms from cyanobacteria to plants. In this study, 10 CsaFBN genes were identified in genomic DNA sequences of cucumber (Chinese long and Gy14) through database searches ...
Inyoung Kim   +5 more
doaj   +1 more source

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