Results 141 to 150 of about 1,871 (159)
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Regulation of fibrillin-1 gene expression by Sp1
Gene, 2013Mutations in the fibrillin-1 gene (FBN1) cause Marfan Syndrome (MFS), a hereditary disorder of connective tissue. The transcription of FBN1 has been reported to be driven by a short ultraconserved region (SUPR) in the 5' untranslated exon A of FBN1, but the nature of other factors involved in FBN1 gene regulation has not been clarified.
Gao, Guo +3 more
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2017
Bindegewebe bezeichnet verschiedene Gewebetypen im Korper, die auf unterstutzende Aufgaben spezialisiert sind. Diese Gewebetypen enthalten relativ wenige Korperzellen sowie das biologische Material zwischen den Zellen, die so genannte extrazellulare Matrix.
Karina A. Zeyer, Dieter P. Reinhardt
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Bindegewebe bezeichnet verschiedene Gewebetypen im Korper, die auf unterstutzende Aufgaben spezialisiert sind. Diese Gewebetypen enthalten relativ wenige Korperzellen sowie das biologische Material zwischen den Zellen, die so genannte extrazellulare Matrix.
Karina A. Zeyer, Dieter P. Reinhardt
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PARTIAL CLONING AND SEQUENCING OF CHICK FIBRILLIN-1 cDNA
In Vitro Cellular & Developmental Biology - Animal, 2000The recent identification of numerous matrix genes and gene products has allowed a detailed examination of their roles in development. Two of these extracellular matrix proteins, fibrillin-1 and fibrillin-2, are components of the elastin-associated microfibrils.
G, Zhou +4 more
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Immobilisation of a fibrillin-1 fragment enhances the biocompatibility of PTFE
Colloids and Surfaces B: Biointerfaces, 2014Current vascular biomaterials exhibit poor biocompatibility characterised by failure to promote endothelialisation, predisposition to neoinitmal hyperplasia and excessive thrombogenicity. Fibrillin-1, a major constituent of microfibrils is associated with elastic fibres in the arterial wall.
Hajian, Hamid +11 more
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Influence of fibrillin-1 genotype on the aortic stiffness in men
Journal of Applied Physiology, 2005Aortic stiffness is a predictor of cardiovascular mortality. The mechanical properties of the arterial wall depend on the connective tissue framework, with variation in fibrillin-1 and collagen I genes being associated with aortic stiffness and/or pulse pressure elevation.
J T, Powell +4 more
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Fibrillin-1 Protein in Tight Skin Mice and Scleroderma
Clinical Reviews in Allergy & Immunology, 2000Scleroderma (SSc) is a complex and clinically heterogenous disease of unknown origin, in which both genetic and environmental factors appear to be implicated. In addition to skin, other internal organs, including lung, heart, intestine, and kidney, can be affected.
C, Bona, S, Saito
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Relaxin modulates fibrillin-2, but not fibrillin-1, gene expression by human dermal fibroblasts
2001Fibrillins-1 and -2 are the main constituents of extracellular elastic microfibrils and contribute significantly to tissue integrity and elasticity [1]. Fibrillin-1 (FBN-1) was first discovered from the medium of cultured human dermal fibroblasts [2] and was identified as part of elastic-associated and non-elastic tissue microfibrils [3,4].
Chrishan S. Samuel +2 more
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Immunohistochemical expression of Fibrillin-1 in idiopathic epiretinal membranes
Graefe's Archive for Clinical and Experimental OphthalmologyTo investigate the expression patterns of Fibrillin-1 in idiopathic epiretinal membranes (iERM) and identify Fibrillin-1-secreting cells.iERM samples were collected via standard 27-gauge vitrectomy and subsequently subjected to flat-mount immunohistochemistry with double staining for the following markers: Fibrillin-1, glial acidic fibrillary protein ...
Luu Viet Tien +4 more
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