Results 21 to 30 of about 7,077 (251)

Fibrillins 1 and 2 Perform Partially Overlapping Functions during Aortic Development [PDF]

Journal of Biological Chemistry, 2005
Fibrillin-rich microfibrils are extracellular assemblies that impart structural properties to the connective tissue. To elucidate the contribution of fibrillin-rich microfibrils to organogenesis, we have examined the vascular phenotype of a newly created
Luca Carta, Lygia da Veiga Pereira, Emilio Arteaga‐Solis, Sui Lee‐Arteaga, Brett A. Lenart, Barry Starcher, Christian Merkel, M. A. Sukoyan, Alexander Kerkis, Noriko Hazeki, Douglas R. Keene, Lynn Y. Sakai, Francesco Ramirez   +12 more
openalex   +2 more sources

Latent Transforming Growth Factor β-binding Protein 1 Interacts with Fibrillin and Is a Microfibril-associated Protein [PDF]

Journal of Biological Chemistry, 2003
Latent transforming growth factor β-binding protein 1 (LTBP-1) targets latent complexes of transforming growth factor β to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms.
Zenzo Isogai, Robert N. Ono, Shin Ushiro, Douglas R. Keene, Yan Chen, Roberta Mazzieri, Noé L. Charbonneau, Dieter P. Reinhardt, Daniel B. Rifkin, Lynn Y. Sakai   +9 more
openalex   +2 more sources

Fibrillin and the eye [PDF]

British Journal of Ophthalmology, 2000
The glycoprotein fibrillin is the principal component of the ciliary zonule and has an important role in the strength and elasticity of ocular connective tissues. Fibrillin polymers form the structural scaffold of extensible microfibrils1-3 which are present in ocular elastic tissues and are arranged in parallel bundles to form the zonular fibres.4 ...
Cay M. Kielty, David McLeod, Jane Ashworth   +2 more
openaire   +3 more sources

Fibrillines et fibrillinopathies [PDF]

médecine/sciences, 1996
Microfibrils contain a variety of proteins, the most prominent of which are the two fibrillins. Fibrillins are large glycoproteins (320 kDa) ubiquitously distributed in connective tissues. Together with amorphous elastin, fibrillin-containing microfibrils form the elastic fibers.
Collod-Beroud, Gwenaëlle, Boileau, Catherine   +1 more
openaire   +3 more sources

Fibrillin: from microfibril assembly to biomechanical function [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2002
Fibrillins form the structural framework of a unique and essential class of extracellular microfibrils that endow dynamic connective tissues with long–range elasticity. Their biological importance is emphasized by the linkage of fibrillin mutations to Marfan syndrome and related connective tissue disorders, which are associated with severe ...
Cay M. Kielty, Clair Baldock, David M. Lee, Matthew J. Rock, Jane Ashworth, C. Adrian Shuttleworth   +5 more
openalex   +9 more sources

Transcriptome analysis of skin fibroblasts with dominant negative COL3A1 mutations provides molecular insights into the etiopathology of vascular Ehlers-Danlos syndrome. [PDF]

PLoS ONE, 2018
Vascular Ehlers-Danlos syndrome (vEDS) is a dominantly inherited connective tissue disorder caused by mutations in the COL3A1 gene that encodes type III collagen (COLLIII), which is the major expressed collagen in blood vessels and hollow organs.
Nicola Chiarelli, Giulia Carini, Nicoletta Zoppi, Marco Ritelli, Marina Colombi   +4 more
doaj   +1 more source

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation [PDF]

, 2015
MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly.
Heumüller, Stefanie E, Holm, Anne T, Holmskov, Uffe, Moeller, Jesper B, Moestrup, Soren K, Pilecki, Bartosz, Schlosser, Anders, Sengle, Gerhard, Sorensen, Grith L, Wallis, Russell, Wohl, Alexander P, Zuk, Alexandra V   +11 more
core   +1 more source

The N-terminal Part of Arabidopsis thaliana Starch Synthase 4 Determines the Localization and Activity of the Enzyme [PDF]

, 2016
Starch synthase 4 (SS4) plays a specific role in starch synthesis because it controls the number of starch granules synthesized in the chloroplast and is involved in the initiation of the starch granule.
Mérida Berlanga, Ángel, Ragel de la Torre, Paula, Raynaud, Sandy   +2 more
core   +1 more source

Arabidopsis thaliana plastoglobule‐associated fibrillin 1a interacts with fibrillin 1b in vivo [PDF]

FEBS Letters, 2014
Plant fibrillins are a well‐conserved protein family found in the plastids of all photosynthetic organisms, where they perform a wide range of functions. A number of these proteins have been suggested to be involved in the maintenance of thylakoids and the formation of plastoglobules, preventing their coalescence and favoring their clustering via an as‐
Gámez Arjona, Francisco M., Raynaud, Sandy, Mérida Berlanga, Ángel, Concepción, Juan Carlos de la   +3 more
openaire   +5 more sources

Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing [PDF]

, 2017
Tendon is composed of fascicles bound together by the interfascicular matrix (IFM). Energy storing tendons are more elastic and extensible than positional tendons; behaviour provided by specialisation of the IFM to enable repeated interfascicular sliding
A Heinz, AJ Viera, B Vrhovski, C Thorpe, C Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, D Bedell-Hogan, EL Batson, F Ramirez, H Birch, H Oxlund, H Tempfer, HL Birch, IM Braverman, J Fallon, JA Foster, JA Foster, JA Pierce, JE Wagenseil, JF Innes, K Kubo, KD Smith, L Nimeskern, L Robert, L Robert, M Akagawa, M Benjamin, M Luisetti, MJ Sherratt, P Berens, P Kannus, PPY Lui, R Alexander, R Ker, SA Fenwick, SE Greenwald, SG Dakin, T Watanabe, TB Csóka, TC Lee, TM Grant, TM Grant, Z Gunja-Smith, Z Liu   +48 more
core   +3 more sources