Results 101 to 110 of about 202,201 (346)

Reinforcement of polymeric structures with asbestos fibrils [PDF]

, 1970
Investigation determines structural potential of asbestos fibrils. Methods are developed for dispersing macrofibers of the asbestos into colloidal-sized ultimate fibrils and incorporating these fibrils in matrices without causing ...
Schwartz, A. M., Rader, C. A.
core  

Equilibrium dynamics of wild type hIAPP fibrils.

, 2014
(a) Conformations of polymorphic hIAPP fibrils at time of 60 ns obtained from explicit water MD simulation. (b) Root-mean-square distance (RMSD) for polymorphic hIAPP fibrils as a function of time.
Sungsoo Na (262181), Myeongsang Lee (523341), Jae In Kim (523342), Gwonchan Yoon (523340), Kilho Eom (262191)   +4 more
core   +1 more source

Micromechanical bending of single collagen fibrils using atomic force microscopy [PDF]

, 2007
A new micromechanical technique was developed to study the mechanical properties of single collagen fibrils. Single collagen fibrils, the basic components of the collagen fiber, have a characteristic highly organized structure. Fibrils were isolated from
Bennink, Martin L., Dijkstra, Pieter J., van der Werf, Kees, Kees O. van der Werf, Koopman, Bart F J M, Bennink, Martin L, Vinod Subramaniam, Feijen, Jan, van der Werf, Kees O, Koopman, Hubertus F.J.M.; id_orcid, Bart F.J.M. Koopman, Jan Feijen, Subramaniam, Vinod, Pieter J. Dijkstra, Yang, Lanti, Dijkstra, Pieter J, Lanti Yang, Martin L. Bennink   +17 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Localized Amyloidosis of the Oral Cavity: A Rare Clinical Entity

Clinical Case Reports
Amyloidosis is a complex disease which rarely affects the oral cavity. While localized and systemic variants have a similar clinical presentation, these entities differ vastly in their natural history and prognosis.
Brian Maloney, Veronica Fisher, Claire M. Healy   +2 more
doaj   +1 more source

Impact of covalent or non-covalent bound epigallocatechin-3-gallate (EGCG) on assembly, physicochemical characteristics and digestion of ovotransferrin fibrils

, 2020
The objectives of the present study were to investigate impact of covalent or non-covalent bound (−)-epigallocatechin-3-gallate (EGCG) on ovotransferrin (OVT) fibrils.
Zi-Hao Wei, Qing-Rong Huang
semanticscholar   +1 more source

AFM analysis of fibrils immobilised on a C1 chip.

, 2013
Mature fibrils were briefly sonicated prior to immobilisation on C1 chip followed by continuous polymerisation with free monomers until the total mass doubled.
Kristoffer Brännström (343000), Anders Öhman (343001), Anders Olofsson (343002)   +2 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Atrial fibrillation [PDF]

Canadian Medical Association Journal, 2004
Atrial fibrillation (AF) is the most common sustained dysrhythmia in adults. It is ironic, then, that although mechanisms and effective treatments for most other supraventricular tachyarrhythmias have been discovered, AF remains incompletely understood and poorly treated.
George D, Veenhuyzen, Christopher S, Simpson, Hoshiar, Abdollah   +2 more
openaire   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source