Results 221 to 230 of about 202,201 (346)

Beyond Primary Nucleation: Molecular Basis of Peptide Crystal Secondary Nucleation at Soft Interface

Advanced Functional Materials, EarlyView.
High spatiotemporal‐resolution atomic force microscopy directly resolved peptide secondary nucleation (SN) and growth characteristics and mechanisms on HOPG. The landscape of peptide nucleation sites, growth dynamics, molecular‐scale structures, phase transitions, and cross‐seeding processes were realized.
Linhao Sun, Abilesh Kumar, Ayhan Yurtsever   +2 more
wiley   +1 more source

Architectural Tuning of Bouligand Electrospun Laminates Enables Coupled Mechanical Robustness and Electromechanical Sensing

Advanced Functional Materials, EarlyView.
Bioinspired Bouligand architectures are translated into biodegradable polymer laminates with integrated sensing, revealing how structural design governs multifunctional performance. A 20° interlayer rotation optimizes strength, flexibility, and electromechanical response, while embedded nanotube networks enable real‐time damage detection and wearable ...
Piotr K. Szewczyk, Daniel P. Ura, Michał Kopacz, Katarzyna Marszalik, Urszula Stachewicz   +4 more
wiley   +1 more source

Brain-seeded 42-residue Amyloid-β Fibrils That Resemble Fibrils Directly Extracted From Alzheimer's Disease Brain Tissue. [PDF]

J Mol Biol
Thurber KR, Lee M, Tycko R.
europepmc   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Vaccines mimicking conformational epitopes on α-synuclein fibrils provide immunity to Parkinson's disease. [PDF]

Brain
Ma L, Reithofer S, Pesch V, Flores-Fernandez JM, Sriraman A, Duckering C, Amidian S, Özdüzenciler P, Müller L, Wille H, Tamgüney G.   +10 more
europepmc   +1 more source

Structure of the cross-β spine of amyloid-like fibrils

Nature, 2005
R. Nelson, M. Sawaya, M. Balbirnie, A. Madsen, C. Riekel, R. Grothe, D. Eisenberg   +6 more
semanticscholar   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Detection of amyloid fibrils in Parkinson’s disease using plasmonic chirality

Proceedings of the National Academy of Sciences of the United States of America, 2018
J. Kumar, Hasier Eraña, Elena López-Martínez, N. Claes, V. Martín, D. M. Solís, S. Bals, A. Cortajarena, J. Castilla, L. Liz-Márzan   +9 more
semanticscholar   +1 more source

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Photo-Switched Catalytic Amyloids. [PDF]

Small
Bhaumik SK, Kunnath SM, Arad E, Nativ-Roth E, Chatterjee A, Batushansky A, Shauloff N, Rapaport H, Jelinek R.   +8 more
europepmc   +1 more source