Results 161 to 170 of about 340,737 (387)

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

open access: yesAdvanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong   +8 more
wiley   +1 more source

Designing the Next Generation of Biomaterials through Nanoengineering

open access: yesAdvanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr.   +3 more
wiley   +1 more source

Biomimetic 3D‐Printed Adaptive Hydrogel Bioadhesives Featuring Superior Infection Resistance for Challenging Tissue Adhesion, Hemostasis, and Healthcare

open access: yesAdvanced Materials, EarlyView.
Biomimetic 3D‐printed hydrogel bioadhesives (PTLAs) are designed to address the limitations of existing bioadhesives, offering solutions for challenging tissue adhesion and enhanced healthcare. These PTLAs feature robust wet/underwater tissue adhesion/sealing, superior freeze/pressure and infection resistance, and adaptive self‐healing/gelling capacity,
Qi Wu   +4 more
wiley   +1 more source

Sonodynamic and Bioorthogonal Sonocatalytic Thrombotic Therapy Based on AIE Cationic Tetranuclear Ir(III) Complex Nanoplatform Guided by NIR‐Chemiluminescence Imaging

open access: yesAdvanced Materials, EarlyView.
AIE‐active tetranuclear Ir(III) complex Ir‐4 as a sonosensitizer/sonocatalyst is formulated into a nanoplatform with an H2S donor. Ir‐4@S‐R NPs achieves combined endogenous NIR chemiluminescence imaging, sonodynamic therapy and release of H2S in situ by a bioorthogonal sonocatalytic reaction in vivo, achieving safe thrombolysis and anti‐inflammatory ...
Zihan Wu   +11 more
wiley   +1 more source

Volumetric 3D Printing and Melt‐Electrowriting to Fabricate Implantable Reinforced Cardiac Tissue Patches

open access: yesAdvanced Materials, EarlyView.
This study presents an implantable reinforced cardiac patch (RCPatch) combining volumetrically 3D‐printed metamaterials with melt‐electrowritten (MEW) meshes. The design integrates tunable stiff polymer structures with soft, cell‐laden hydrogels. The RCPatch withstands suturing, intraventricular pressure, and cardiac contraction in a large animal ...
Lewis S. Jones   +12 more
wiley   +1 more source

Chemical Adjustment of Fibrinolysis

open access: yesPharmaceuticals
Fibrinolysis is the process of the fibrin–platelet clot dissolution initiated after bleeding has been stopped. It is regulated by a cascade of proteolytic enzymes with plasmin at its core.
Alexey M. Shibeko   +4 more
doaj   +1 more source

Bioinspired Smart Nanogels for Rapid Blue Laser‐Activated Hemostasis in Gastrointestinal Bleeding

open access: yesAdvanced Materials, EarlyView.
Waxberry‐inspired branched‐silica nanogel can swiftly stop bleeding upon blue laser endoscopy for gastrointestinal hemostasis in the esophagus, stomach, and duodenum of mini‐pigs. Abstract Gastrointestinal bleeding (GIB) is a critical condition that requires rapid and effective intervention.
Ruijue Dan   +12 more
wiley   +1 more source

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