The Role of Fibrin(ogen) in Wound Healing and Infection Control
Fibrinogen, one of the most abundant plasma proteins playing a key role in hemostasis, is an important modulator of wound healing and host defense against microbes.
Katherine J. Kearney+2 more
semanticscholar +1 more source
Fibrin(ogen) in human disease: both friend and foe
Fibrinogen is an abundant protein synthesized in the liver, present in human blood plasma at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 days. With fibrin, produced by thrombin-mediated cleavage, fibrinogen
Rui Vilar+3 more
semanticscholar +1 more source
Levels of Fibrinogen Variants Are Altered in Severe COVID-19
Background Fibrinogen variants as a result of alternative messenger RNA splicing or protein degradation can affect fibrin(ogen) functions. The levels of these variants might be altered during coronavirus disease 2019 (COVID-19), potentially ...
de Vries de Vries+13 more
doaj +1 more source
Multi-scale strain-stiffening of semiflexible bundle networks [PDF]
Bundles of polymer filaments are responsible for the rich and unique mechanical behaviors of many biomaterials, including cells and extracellular matrices.
Broedersz, C. P.+5 more
core +2 more sources
Quantification of Plasma Fibrinogen Degradation Products in Areca Nut Chewers with and without Oral Submucous Fibrosis [PDF]
Introduction: Fibrinogen degradation products (FDPs) are the products that are released from fibrin/fibrinogen. Recently, it has been observed that these FDPs have been identified in the plasma of OSMF patients. Areca nut being the major aetiological
Sonia Gupta+3 more
doaj +1 more source
Impaired endogenous fibrinolysis at high shear using a point-of-care test in STEMI is associated with alterations in clot architecture [PDF]
© The Author(s) 2019Impaired endogenous fibrinolysis is an adverse prognostic biomarker in acute coronary syndrome (ACS). Abnormally dense in vitro fibrin thrombi have been demonstrated in ACS patients and related to hypofibrinolysis using cumbersome ...
A Undas+12 more
core +3 more sources
Foam-like compression behavior of fibrin networks [PDF]
The rheological properties of fibrin networks have been of long-standing interest. As such there is a wealth of studies of their shear and tensile responses, but their compressive behavior remains unexplored.
Alber, Mark S.+5 more
core +2 more sources
Interference of Monoclonal Gammopathy with Fibrinogen Assay Producing Spurious Dysfibrinogenemia
Abnormal coagulation properties indicative of a dysfibrinogenemia were found in the plasma of an asymptomatic 65-year-old male. An immunoglobulin k light chain was found to interfere with Fg functional assay and coagulation tests (activated partial ...
Francesca Martini+6 more
doaj +1 more source
Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components. [PDF]
Background Proteases expressed in atherosclerotic plaque lesions generate collagen fragments, release glycosaminoglycans (chondroitin sulfate [CS] and dermatan sulfate [DS]) and expose extracellular matrix (ECM) proteins (e.g.
Bóta, Attila+7 more
core +1 more source
PRECIPITATION OF HYBRID HYDROXYAPATITE / AUTOFIBRIN NANOCOMPOSITES
Hybrid composites based on hydroxyapatite and autofibrin were synthesized by precipitation in a medium with pH=9. Soft precipitation conditions and rapid isolation of the composite precipitates favored preservation of a biopolymer matrix of autofibrin ...
I.E. Glazov+5 more
doaj +1 more source