Results 321 to 330 of about 370,815 (388)

Perigraftitis treatment and histology: A case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Currently, the two diagnoses of inflammatory peri‐implant diseases are peri‐implant mucositis and peri‐implantitis. The etiology of peri‐implant mucositis and peri‐implantitis is bacterial colonization of the implant. Thus, removal of the implant should eliminate the infection and allow the inflammation to resolve. However, at least
Jonathan H. Do   +2 more
wiley   +1 more source

Design and Evaluation of Sticky End‐Type Bivalent DNA Aptamers Containing M08s‐1 as Anticoagulant Agents

open access: yesChemMedChem, EarlyView.
Sticky end‐type antithrombin aptamer, composed of two short hybridizable segments, is developed as a potential alternative to conventional anticoagulant drugs. The obtained bivalent aptamer surpasses existing long bivalent aptamers in anticoagulant activity and serum stability, offering advantages in synthesis efficiency and cost‐effectiveness. Aptamer
Maasa Yokomori   +4 more
wiley   +1 more source

Quantitative Model‐Informed Dose Selection for a Milvexian Phase III Study in Patients With Atrial Fibrillation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Milvexian, an activated factor XI inhibitor, is being evaluated in the LIBREXIA phase III program for the prevention of thrombotic events, including in patients with atrial fibrillation (LIBREXIA AF). To guide the selection of a phase III dose regimen for LIBREXIA AF, two main approaches were used: (1) population pharmacokinetics and exposure–response ...
Wangda Zhou   +12 more
wiley   +1 more source

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito   +9 more
wiley   +1 more source

The Use of Fibrin Clot During Meniscus Repair in Young Patients Reduces Clinical Symptom Rates at 12-Month Follow-Up: A Pilot Randomized Controlled Trial. [PDF]

open access: yesMedicina (Kaunas)
Martinkėnienė VB   +6 more
europepmc   +1 more source

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