Results 341 to 350 of about 261,983 (361)
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2005
Fibrinogen is a large, complex, fibrous glycoprotein with three pairs of polypeptide chains linked together by 29 disulfide bonds. It is 45 nm in length, with globular domains at each end and in the middle connected by alpha-helical coiled-coil rods. Both strongly and weakly bound calcium ions are important for maintenance of fibrinogen's structure and
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Fibrinogen is a large, complex, fibrous glycoprotein with three pairs of polypeptide chains linked together by 29 disulfide bonds. It is 45 nm in length, with globular domains at each end and in the middle connected by alpha-helical coiled-coil rods. Both strongly and weakly bound calcium ions are important for maintenance of fibrinogen's structure and
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Blood Reviews, 1991
Fibrin glue is a topical biological adhesive, the effect of which imitates the final stages of coagulation. The glue consists of a solution of concentrated human fibrinogen which is activated by the addition of bovine thrombin and calcium chloride. The resultant clot aids haemostasis and tissue sealing and is completely absorbed during wound healing ...
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Fibrin glue is a topical biological adhesive, the effect of which imitates the final stages of coagulation. The glue consists of a solution of concentrated human fibrinogen which is activated by the addition of bovine thrombin and calcium chloride. The resultant clot aids haemostasis and tissue sealing and is completely absorbed during wound healing ...
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Clinica Chimica Acta, 2002
Soluble fibrin (SF), composed of fibrin monomer (FM) and fibrinogen, is well known to exist in the circulating blood derived from patients with thrombotic diseases, and its quantification is useful to get some information on the state and degree of intravascular coagulation.
Akiei Hamano+4 more
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Soluble fibrin (SF), composed of fibrin monomer (FM) and fibrinogen, is well known to exist in the circulating blood derived from patients with thrombotic diseases, and its quantification is useful to get some information on the state and degree of intravascular coagulation.
Akiei Hamano+4 more
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The Fibrin Intermediate, Its Place in the Fibrinogen‐Fibrin Transformation
Annals of the New York Academy of Sciences, 2001Abstract: Our preceding study indicated that, in course of coagulation of human fibrinogen by thrombin, substantial production of the fibrin intermediate (α‐profibrin) lacking only one fibrinopeptide A (FPA) precedes the formation of α‐fibrin monomer lacking both FPAs.
Gary B. Smejkal+5 more
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Fibrin Stabilization (Factor XIII), Fibrin Structure and Thrombosis
Pathophysiology of Haemostasis and Thrombosis, 2003Factor XIII (FXIII) is a zymogen that is converted into an active transglutaminase (FXIIIa) by the concerted action of thrombin and Ca2+. Its main task is to crosslink alpha-, and gamma-chains of fibrin and alpha2-plasmin inhibitor to fibrin. By this way FXIIIa strengthens fibrin and protects it from the prompt elimination by fibrinolytic system.The ...
László Muszbek+2 more
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THE STRUCTURE OF FIBRINOGEN AND FIBRIN: II. ARCHITECTURE OF THE FIBRIN CLOT*
Annals of the New York Academy of Sciences, 1983Our present low resolution model for fibrinogen based on electron microscopy and x-ray diffraction data has been described by Cohen et al. A unique aspect of the structural analysis of fibrous proteins is that the molecular packing in ordered arrays reflects biologically significant intermolecular interactions.
Carolyn Cohen+2 more
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Fibrin deposition and fibrin degradation products in atherosclerotic plaques
Thrombosis Research, 1994Soluble fibrin/fibrinogen-related antigens and insoluble fibrin are present in virtually all samples of human aortic intima. Components of the soluble fraction were identified by SDS-PAGE and immunoblotting with specific antisera. The fibrinogen was characterized by increased proportions of low molecular mass (Mr) species (300 and 280 kD), the FDP by ...
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2011
Fibrin, derived from key proteins involved in blood clotting (fibrinogen and thrombin), is a self-assembling biopolymer. The range of clinical applications and types of procedure that incorporate fibrin sealants is expanding. While fibrin sealants have been initially used for their hemostasis and tissue sealing properties, they have also been recently ...
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Fibrin, derived from key proteins involved in blood clotting (fibrinogen and thrombin), is a self-assembling biopolymer. The range of clinical applications and types of procedure that incorporate fibrin sealants is expanding. While fibrin sealants have been initially used for their hemostasis and tissue sealing properties, they have also been recently ...
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