Results 11 to 20 of about 168,560 (263)
A central role for fibrinogen in promoting microglial repair of the hypoxia-disrupted blood-brain barrier [PDF]
Journal of NeuroinflammationBuilding on our previous finding that a small fibrinogen peptide inhibits microglial repair of the hypoxia-disrupted blood-brain barrier (BBB), we directly evaluated the importance of fibrinogen in this process by studying these events in fibrinogen ...
Sebok K. Halder +2 more
doaj +2 more sources
Renal Failure, 2023 Background and aim Plasma fibrinogen has been proven to be significantly associated with cardiovascular mortality in patients undergoing peritoneal dialysis (PD).
Yun Chen +6 more
doaj +1 more source
Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk
Haematologica, 2020 Complement C3 binds fibrinogen and compromises fibrin clot lysis thereby enhancing thrombosis risk. We investigated the role of fibrinogen-C3 interaction as a novel therapeutic target to reduce thrombosis risk by analysing: i) consistency in the ...
Rhodri J. King +12 more
doaj +1 more source
The Saudi Journal of Gastroenterology, 2014 The mutation γ375Arg → Trp (fibrinogen Aguadilla) is one of four mutations (Brescia, Aguadilla, Angers, and AI duPont) capable of causing hepatic storage of fibrinogen.
Abdulrahman Al-Hussaini +6 more
doaj +1 more source
DNA methylation profiling of the fibrinogen gene landscape in human cells and during mouse and zebrafish development. [PDF]
PLoS ONE, 2013 The fibrinogen genes FGA, FGB and FGG show coordinated expression in hepatocytes. Understanding the underlying transcriptional regulation may elucidate how their tissue-specific expression is maintained and explain the high variability in fibrinogen ...
Silja Vorjohann +6 more
doaj +1 more source
Fibrinogen metabolic responses to trauma
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2009 Coagulation complications are significant contributors to morbidity and mortality in trauma patients. Although the lethal triad of hypothermia, acidosis and coagulopathy has been recognized for over a decade, the underlying mechanisms related to the ...
Martini Wenjun
doaj +1 more source
Prognostic Impact of Pretreatment Plasma Fibrinogen in Patients with Locally Advanced Oral and Oropharyngeal Cancer. [PDF]
PLoS ONE, 2016 We aimed to determine the prognostic significance of pretreatment plasma fibrinigen in patients with oral and oropharyngeal squamous cell carcinoma (OOSCC).A cohort of 183 patients with locally advanced OOSCC receiving preoperative chemoradiotherapy was ...
Daniel Holzinger +10 more
doaj +1 more source
Journal of Clinical Pathology, 1965 Platelet fibrinogen has been studied in normal, thrombasthenic, and hypofibrinogenaemic subjects. It has been differentiated into adsorbed (plasma) and extractable (intraplatelet) fractions. Isotopic studies suggest that exchange does not occur between intraplatelet and plasma fibrinogen and it appears possible that the intra-platelet fraction may be ...
P A, Castaldi, J, Caen
openaire +2 more sources
Risk Factors for Postoperative Fibrinogen Deficiency after Surgical Removal of Intracranial Tumors.
PLoS ONE, 2015 Higher levels of fibrinogen, a critical element in hemostasis, are associated with increased postoperative survival rates, especially for patients with massive operative blood loss.
Naili Wei +10 more
doaj +1 more source
Respiratory Research, 2021 Background Fibrinogen is the first qualified prognostic/predictive biomarker for exacerbations in patients with chronic obstructive pulmonary disease (COPD).
Dave Singh +14 more
doaj +1 more source