Results 11 to 20 of about 171,231 (260)
Hypochlorite-induced aggregation of fibrinogen underlies a novel antioxidant role in blood plasma
Redox Biology, 2021 Fibrinogen, a major constituent of blood plasma, is highly susceptible to reaction with biological oxidants. It has been proposed that fibrinogen plays a role in antioxidant defence, but oxidation of fibrinogen is also known to disrupt normal blood ...
Noralyn Mañucat-Tan +5 more
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Renal Failure, 2023 Background and aim Plasma fibrinogen has been proven to be significantly associated with cardiovascular mortality in patients undergoing peritoneal dialysis (PD).
Yun Chen +6 more
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Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk
Haematologica, 2020 Complement C3 binds fibrinogen and compromises fibrin clot lysis thereby enhancing thrombosis risk. We investigated the role of fibrinogen-C3 interaction as a novel therapeutic target to reduce thrombosis risk by analysing: i) consistency in the ...
Rhodri J. King +12 more
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The Saudi Journal of Gastroenterology, 2014 The mutation γ375Arg → Trp (fibrinogen Aguadilla) is one of four mutations (Brescia, Aguadilla, Angers, and AI duPont) capable of causing hepatic storage of fibrinogen.
Abdulrahman Al-Hussaini +6 more
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DNA methylation profiling of the fibrinogen gene landscape in human cells and during mouse and zebrafish development. [PDF]
PLoS ONE, 2013 The fibrinogen genes FGA, FGB and FGG show coordinated expression in hepatocytes. Understanding the underlying transcriptional regulation may elucidate how their tissue-specific expression is maintained and explain the high variability in fibrinogen ...
Silja Vorjohann +6 more
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Prognostic Impact of Pretreatment Plasma Fibrinogen in Patients with Locally Advanced Oral and Oropharyngeal Cancer. [PDF]
PLoS ONE, 2016 We aimed to determine the prognostic significance of pretreatment plasma fibrinigen in patients with oral and oropharyngeal squamous cell carcinoma (OOSCC).A cohort of 183 patients with locally advanced OOSCC receiving preoperative chemoradiotherapy was ...
Daniel Holzinger +10 more
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Fibrinogen metabolic responses to trauma
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2009 Coagulation complications are significant contributors to morbidity and mortality in trauma patients. Although the lethal triad of hypothermia, acidosis and coagulopathy has been recognized for over a decade, the underlying mechanisms related to the ...
Martini Wenjun
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Risk Factors for Postoperative Fibrinogen Deficiency after Surgical Removal of Intracranial Tumors.
PLoS ONE, 2015 Higher levels of fibrinogen, a critical element in hemostasis, are associated with increased postoperative survival rates, especially for patients with massive operative blood loss.
Naili Wei +10 more
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The Effect of Reagents Mimicking Oxidative Stress on Fibrinogen Function
The Scientific World Journal, 2013 Fibrinogen is one of the plasma proteins most susceptible to oxidative modification. It has been suggested that modification of fibrinogen may cause thrombotic/bleeding complications associated with many pathophysiological states of organism.
Jana Štikarová +6 more
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Respiratory Research, 2021 Background Fibrinogen is the first qualified prognostic/predictive biomarker for exacerbations in patients with chronic obstructive pulmonary disease (COPD).
Dave Singh +14 more
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